INHIBITION OF ADHERENCE OF CANDIDA-ALBICANS TO ACRYLIC BY A CHITIN DERIVATIVE

被引：11

作者：

SEGAL, E

KREMER, I

DAYAN, D

机构：

[1] Department of Human Microbiology - Sackler Faculty of Medicine, Tel Aviv University Ramat Aviv, Tel Aviv

[2] Section of Oral Pathology and Oral Medicine - The Maurice, and Gabriela Goldschleger School of Dental Medicine, Tel Aviv University, Tel Aviv

来源：

EUROPEAN JOURNAL OF EPIDEMIOLOGY | 1992年 / 8卷 / 03期

关键词：

CANDIDA; ADHERENCE; ACRYLIC;

D O I：

10.1007/BF00158567

中图分类号：

R1 [预防医学、卫生学];

学科分类号：

1004 ; 120402 ;

摘要：

The purpose of this study was to assess the effect of a chitin derivative (CSE) on the adherence of Candida albicans to acrylic. Fungal adherence to acrylic dentures is considered an essential step in the development of denture stomatitis. Adherence of C albicans to acrylic pieces (5 x 5mm) was assessed microscopically using a calibrated ocular objective and expressed as number of adherent yeasts/mm2 of acrylic. CSE was prepared from commercial chitin (crab shell) and from chitin isolated from C. albicans blastospores. The effect of both CSE types on the adherence of C albicans to acrylic was examined in two experimental systems: CSE present during the adherence assay and acrylic pieces pretreated with CSE prior to the assay. Both CSE types exerted a significant inhibitory effect when tested in the two experimental systems. These findings are significant for possible prevention of denture stomatitis.

引用

页码：350 / 355

页数：6

共 22 条

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