A FACILE SYNTHESIS OF 6-ALKYL-6,7-DIHYDRO-5H-DIBENZ[C,E]AZEPINES - POTENT HYPOLIPIDEMICS

被引：1
作者：
AKULA, MR
KABALKA, GW
机构：
[1] UNIV TENNESSEE, DEPT CHEM, KNOXVILLE, TN 37996 USA
[2] UNIV TENNESSEE, DEPT RADIOL, KNOXVILLE, TN 37996 USA
来源：
SYNTHETIC COMMUNICATIONS | 1995年 / 25卷 / 23期
关键词：
D O I：
10.1080/00397919508011465
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
6-Alkyl-6,7-dihydro-5H-dibenz[c,e]azepines were synthesized in two steps in 63-88% overall yield by utilizing an efficient borane-tetrahydrofuran reduction of imides.
引用
收藏
页码：3901 / 3906
页数：6
相关论文
共 50 条
[31]   5H-DIBENZ[B,F]AZEPINES .6. KINETICS OF PALLADIUM-CATALYZED TRANSFER DEHYDROGENATION OF 10,11-DIHYDRO-5H-DIBENZ[D,F]AZEPINE [J].
GALAMB, V ;
JOO, F ;
KOHEGYI, I .
JOURNAL OF CHEMICAL RESEARCH-S, 1995, (06) :216-217
[32]   EFFECTS OF A NEW DIBENZAZEPINE DERIVATIVE, RO 2-3248, 6-ALLYL-6,7-DIHYDRO-5H-DIBENZ[C,E]AZEPINE PHOSPHATE, UPON THE BLOOD FLOW, THE PERIPHERAL RESISTANCE AND THE RESPONSE TO INJECTIONS OF EPINEPHRINE OF THE INNERVATED HIND LIMB OF THE DOG [J].
MOORE, PE ;
RICHARDSON, AW ;
GREEN, HD .
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS, 1952, 106 (01) :14-23
[33]   Synthesis and functionalization of 6,7-dihydro-5H-pyrrolo[1,2-c]imidazole [J].
Lysenko, Viacheslav ;
Portiankin, Anton ;
Shvydenko, Tetiana ;
Shvydenko, Kostiantyn ;
Shishkina, Svitlana ;
Kostyuk, Aleksandr .
SYNTHETIC COMMUNICATIONS, 2023, 53 (09) :615-624
[34]   Iron-catalyzed alkyne-carbonyl metathesis for the synthesis of 6,7-dihydro-5H-dibenzo[c,e]azonines [J].
Chakraborty, Baitan ;
Jana, Umasish .
ORGANIC & BIOMOLECULAR CHEMISTRY, 2021, 19 (48) :10549-10553
[35]   SYNTHESIS OF 6,7-DIHYDRO-1H-BENZO[B]AZONINES VIA ELECTROCYCLIZATION OF 4,5-DIHYDRO-1H-BENZO[B]AZEPINES [J].
NISOLE, C ;
URIAC, P ;
HUET, J .
JOURNAL OF HETEROCYCLIC CHEMISTRY, 1989, 26 (06) :1719-1721
[36]   MECHANISTIC ASPECTS OF OXIDATION OF N-SUBSTITUTED 5H-DIBENZ[C,E]AZEPINES BY ALDEHYDE OXIDASE [J].
THOMAS, HG ;
RUENITZ, PC .
JOURNAL OF HETEROCYCLIC CHEMISTRY, 1984, 21 (04) :1057-1062
[37]   SYNTHESIS OF 5,7-DIOXO-6-HALOGENOPHENYL-6,7-DIHYDRO-5H-DIBENZO[A,C]CYCLOHEPTENE DERIVATIVES [J].
NEDEV, HN ;
STOYANOV, NM ;
MINCHEV, S ;
ALEKSIEV, BV .
COLLECTION OF CZECHOSLOVAK CHEMICAL COMMUNICATIONS, 1992, 57 (05) :1081-1084
[38]   VASODILATOR AND ADRENERGIC BLOCKING ACTION OF 6-ALLYL-6,7-DIHYDRO-5-DIBENZ[C,E] AZEPINE PHOSPHATE (RO-2-3248) [J].
MOORE, PE ;
RICHARDSON, AW ;
GREEN, HD .
FEDERATION PROCEEDINGS, 1952, 11 (01) :377-377
[39]   Synthesis of substituted 10,11-dihydro-5H-dibenz[b,f]azepines;: Key synthons in syntheses of pharmaceutically active compounds [J].
Jorgensen, TK ;
Andersen, KE ;
Lau, J ;
Madsen, P ;
Huusfeldt, PO .
JOURNAL OF HETEROCYCLIC CHEMISTRY, 1999, 36 (01) :57-64
[40]   A New Approach for the Synthesis of 6,7-Dihydro-5H-Cyclopenta[b]pyridine [J].
Zhou, Jinhua ;
Gao, Haili ;
Sun, Hanzhou ;
Wu, Yuxiong .
ADVANCES IN CHEMICAL, MATERIAL AND METALLURGICAL ENGINEERING, PTS 1-5, 2013, 634-638 :1211-1214
12345