BIOLOGICAL AND CHEMICAL INVESTIGATION OF DRAGONS BLOOD FROM CROTON SPECIES OF SOUTH-AMERICAN .3. CLERODANE DITERPENOIDS FROM CROTON-LECHLERI

被引：28

作者：

CAI, Y ^{[1
]}

CHEN, ZP ^{[1
]}

PHILLIPSON, JD ^{[1
]}

机构：

[1] UNIV LONDON, SCH PHARM, DEPT PHARMACOGNOSY, LONDON, ENGLAND

来源：

PHYTOCHEMISTRY | 1993年 / 34卷 / 01期

关键词：

CROTON-LECHLERI; EUPHORBIACEAE; DRAGONS BLOOD; SANGRE-DE-GRADO; DITERPENOIDS; KORBERIN-A; KORBERIN-B; CLERODANE;

D O I：

10.1016/S0031-9422(00)90816-1

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Further chemical examination of the constituents in the bark of Croton lechleri led to isolation of two new diterpenoidal compounds, korberin A and korberin B. Their structure was elucidated by H-1 and C-13 NMR spectroscopic methods, and they were shown to be diterpenoid lactones with the clerodane skeleton. Their antibacterial activity was tested using a direct bioautographic TLC assay.

引用

页码：265 / 268

页数：4

共 8 条

[1] A FURANOID DITERPENE FROM TINOSPORA-MALABARICA [J].

ATTAURRAHMAN ;

ALI, SS ;

AHMAD, S ;

CHOUDHARY, MI .

PHYTOCHEMISTRY, 1992, 31 (09) :3155-3157

[2] BIOLOGICAL AND CHEMICAL INVESTIGATION OF DRAGONS BLOOD FROM CROTON SPECIES OF SOUTH-AMERICA .1. POLYPHENOLIC COMPOUNDS FROM CROTON-LECHLERI [J].

CAI, Y ;

EVANS, FJ ;

ROBERTS, MF ;

PHILLIPSON, JD ;

ZENK, MH ;

GLEBA, YY .

PHYTOCHEMISTRY, 1991, 30 (06) :2033-2040

[3]

CAI Y, 1993, IN PRESS PHYTOCHEMIS

[4] A DIRECT BIOAUTOGRAPHIC TLC ASSAY FOR COMPOUNDS POSSESSING ANTIBACTERIAL ACTIVITY [J].

HAMBURGER, MO ;

CORDELL, GA .

JOURNAL OF NATURAL PRODUCTS, 1987, 50 (01) :19-22

[5] STEREOCHEMISTRY OF CIS-CLERODANE DITERPENES [J].

MANABE, S ;

NISHINO, C .

TETRAHEDRON, 1986, 42 (13) :3461-3470

[6]

MIYASE T, 1981, CHEM PHARM BULL, V29, P3561

[7] THE C-12 AND C-20 CONFIGURATIONS OF SOME NEOCLERODANE DITERPENOIDS ISOLATED FROM TEUCRIUM SPECIES [J].

PASCUAL, C ;

FERNANDEZ, P ;

GARCIAALVAREZ, MC ;

MARCO, JL ;

FERNANDEZGADEA, F ;

DELATORRE, MC ;

HUESORODRIGUEZ, JA ;

RODRIGUEZ, B ;

BRUNO, M ;

PATERNOSTRO, M ;

PIOZZI, F ;

SAVONA, G .

PHYTOCHEMISTRY, 1986, 25 (03) :715-718

[8] DITERPENES FROM NARDOPHYLLUM-LANATUM [J].

ZDERO, C ;

BOHLMANN, F ;

NIEMEYER, HM .

PHYTOCHEMISTRY, 1990, 29 (04) :1227-1230

← 1 →