BIOLOGICAL AND CHEMICAL INVESTIGATION OF DRAGONS BLOOD FROM CROTON SPECIES OF SOUTH-AMERICAN .3. CLERODANE DITERPENOIDS FROM CROTON-LECHLERI

被引：28
作者：
CAI, Y [1 ]
CHEN, ZP [1 ]
PHILLIPSON, JD [1 ]
机构：
[1] UNIV LONDON, SCH PHARM, DEPT PHARMACOGNOSY, LONDON, ENGLAND
来源：
PHYTOCHEMISTRY | 1993年 / 34卷 / 01期
关键词：
CROTON-LECHLERI; EUPHORBIACEAE; DRAGONS BLOOD; SANGRE-DE-GRADO; DITERPENOIDS; KORBERIN-A; KORBERIN-B; CLERODANE;
D O I：
10.1016/S0031-9422(00)90816-1
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Further chemical examination of the constituents in the bark of Croton lechleri led to isolation of two new diterpenoidal compounds, korberin A and korberin B. Their structure was elucidated by H-1 and C-13 NMR spectroscopic methods, and they were shown to be diterpenoid lactones with the clerodane skeleton. Their antibacterial activity was tested using a direct bioautographic TLC assay.
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页码：265 / 268
页数：4
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