The role of regulatory T cells (Treg) in autoimmunity

被引：0
|
作者：
Zaleska, Isaura [1 ]
Wawrzyszyn, Marta [1 ]
Chelmonska-Soyta, Anna [1 ,2 ]
机构：
[1] Uniwersytet Przyrodniczy we Wroclawiu, Wydzial Medycyny Weterynaryjnej Katedra Immunolog, Wroclaw, Poland
[2] Zaklad Terapii Eksperymentalnej we Wroclawiu, Instytut Immunologii Terapii Doswiadczalnej PAN, Wroclaw, Poland
来源：
ALERGIA ASTMA IMMUNOLOGIA | 2012年 / 17卷 / 04期
关键词：
regulatory T cells; multiple sclerosis; autoimmunity; rheumatoid arthritis;
D O I：
暂无
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
Although regulatory T cells (Treg) represent only 5-10% of CD4 + cells, their suppressor activity in the body focused on autoreactive lymphocytes diminished inflammatory reactions during the course of autoimmune diseases. Presently, numerous studies indicate that Treg cells may be the target or therapeutic tool of intervention in autoimmune diseases. The article presents current information regarding function of Treg and their participation in multiple sclerosis and rheumatoid arthritis in man and in corresponding animal models of the diseases.
引用
收藏
页码：190 / 196
页数：7
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