SPATIAL DISCONTINUITIES IN HUMAN-IMMUNODEFICIENCY-VIRUS TYPE-1 QUASI-SPECIES DERIVED FROM EPIDERMAL LANGERHANS CELLS OF A PATIENT WITH AIDS AND EVIDENCE FOR DOUBLE INFECTION

被引：55
|
作者：
SALA, M
ZAMBRUNO, G
VARTANIAN, JP
MARCONI, A
BERTAZZONI, U
WAINHOBSON, S
机构：
[1] INST PASTEUR,UNITE RETROVIROL MOLEC,F-75724 PARIS,FRANCE
[2] UNIV MODENA,DEPT DERMATOL,I-41100 MODENA,ITALY
[3] CNR,IST GENET BIOCHIM EVOLUZIONIST,I-27100 PAVIA,ITALY
来源：
JOURNAL OF VIROLOGY | 1994年 / 68卷 / 08期
关键词：
D O I：
10.1128/JVI.68.8.5280-5283.1994
中图分类号：
Q93 [微生物学];
学科分类号：
071005 ; 100705 ;
摘要：
A nonhomogeneous spatial distribution of human immunodeficiency virus type 1 quasispecies was observed for epidermal Langerhans cells purified from skin patches taken from a patient with AIDS soon after death. Each patch presented a unique collection of sequences, distinct from those of juxtaposed patches or those derived from the other leg. Infection of Langerhans cells by virus from underlying T cells in the dermis might explain this partition. The analysis revealed the presence of two distinct cocirculating viral strains, indicating double infection.
引用
收藏
页码：5280 / 5283
页数：4
相关论文
共 50 条
  • [21] HUMAN-IMMUNODEFICIENCY-VIRUS TYPE-1 INFECTION OF NEURAL XENOGRAFTS
    CVETKOVICH, TA
    LAZAR, E
    BLUMBERG, BM
    SAITO, Y
    ESKIN, TA
    REICHMAN, R
    BARAM, DA
    DELCERRO, C
    GENDELMAN, HE
    DELCERRO, M
    EPSTEIN, LG
    PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1992, 89 (11) : 5162 - 5166
  • [22] PATHOGENESIS OF PEDIATRIC HUMAN-IMMUNODEFICIENCY-VIRUS TYPE-1 INFECTION
    WILFERT, CM
    WILSON, C
    LUZURIAGA, K
    EPSTEIN, L
    JOURNAL OF INFECTIOUS DISEASES, 1994, 170 (02): : 286 - 292
  • [23] PSYCHONEUROIMMUNOLOGY AND HUMAN-IMMUNODEFICIENCY-VIRUS TYPE-1 INFECTION REVISITED
    GOODKIN, K
    MULDER, CL
    BLANEY, NT
    IRONSON, G
    KUMAR, M
    FLETCHER, MA
    ARCHIVES OF GENERAL PSYCHIATRY, 1994, 51 (03) : 246 - 247
  • [24] MOLECULAR PROFILE OF HUMAN-IMMUNODEFICIENCY-VIRUS TYPE-1 INFECTION IN SYMPTOMLESS PATIENTS AND IN PATIENTS WITH AIDS
    BAGNARELLI, P
    MENZO, S
    VALENZA, A
    MANZIN, A
    GIACCA, M
    ANCARANI, F
    SCALISE, G
    VARALDO, PE
    CLEMENTI, M
    JOURNAL OF VIROLOGY, 1992, 66 (12) : 7328 - 7335
  • [25] EVIDENCE FOR NEUROTOXIC ACTIVITY OF TAT FROM HUMAN-IMMUNODEFICIENCY-VIRUS TYPE-1
    SABATIER, JM
    VIVES, E
    MABROUK, K
    BENJOUAD, A
    ROCHAT, H
    DUVAL, A
    HUE, B
    BAHRAOUI, E
    JOURNAL OF VIROLOGY, 1991, 65 (02) : 961 - 967
  • [26] INFECTION OF ORAL MUCOSAL CELLS BY HUMAN-IMMUNODEFICIENCY-VIRUS TYPE-1 IN SEROPOSITIVE PERSONS
    QURESHI, MN
    BARR, CE
    SESHAMMA, T
    REIDY, J
    POMERANTZ, RJ
    BAGASRA, O
    JOURNAL OF INFECTIOUS DISEASES, 1995, 171 (01): : 190 - 193
  • [27] INFECTION OF CORD BLOOD MONOCYTE-DERIVED MACROPHAGES WITH HUMAN-IMMUNODEFICIENCY-VIRUS TYPE-1
    HO, WZ
    LIOY, J
    SONG, L
    CUTILLI, JR
    POLIN, RA
    DOUGLAS, SD
    JOURNAL OF VIROLOGY, 1992, 66 (01) : 573 - 579
  • [28] ANAPLASTIC ASTROCYTOMA IN ASSOCIATION WITH HUMAN-IMMUNODEFICIENCY-VIRUS TYPE-1 INFECTION
    CARRANA, EJ
    ROSSITCH, E
    MOORE, MR
    FUNKENSTEIN, HH
    AMERICAN JOURNAL OF EMERGENCY MEDICINE, 1990, 8 (06): : 565 - 567
  • [29] LABORATORY TESTS FOR DETECTION OF HUMAN-IMMUNODEFICIENCY-VIRUS TYPE-1 INFECTION
    NUWAYHID, NF
    CLINICAL AND DIAGNOSTIC LABORATORY IMMUNOLOGY, 1995, 2 (06) : 637 - 645
  • [30] INFECTION BY THE HUMAN-IMMUNODEFICIENCY-VIRUS TYPE-1 IN THE PRISON POPULATION IN CATALONIA
    BAYAS, JM
    MARTIN, V
    VIDAL, J
    PUMAROLA, T
    DEANTA, MTJ
    SALLERAS, L
    MEDICINA CLINICA, 1994, 102 (06): : 209 - 212
12345