INVIVO MEASUREMENT OF CEREBRAL OXYGEN-CONSUMPTION AND BLOOD-FLOW USING O-17 MAGNETIC-RESONANCE-IMAGING

被引：98
作者：
PEKAR, J
LIGETI, L
RUTTNER, Z
LYON, RC
SINNWELL, TM
VANGELDEREN, P
FIAT, D
MOONEN, CTW
MCLAUGHLIN, AC
机构：
[1] NIAAA,ROCKVILLE,MD 20852
[2] SEMMELWEIS UNIV MED,H-1085 BUDAPEST 8,HUNGARY
[3] DELFT UNIV TECHNOL,DEPT APPL PHYS,DELFT,NETHERLANDS
[4] UNIV ILLINOIS,DEPT PERFORMING ARTS,CHICAGO,IL 60680
来源：
MAGNETIC RESONANCE IN MEDICINE | 1991年 / 21卷 / 02期
关键词：
D O I：
10.1002/mrm.1910210217
中图分类号：
R8 [特种医学]; R445 [影像诊断学];
学科分类号：
1002 ; 100207 ; 1009 ;
摘要：
We used 17O NMR imaging techniques to measure the H217O concentration in a 0.8‐ml voxel in the cat brain following injection of an arterial bolus of enriched H217O and during inhalation of enriched 17O2. We also measured the H217O concentration in arterial blood during 17O2 inhalation. The data from the first measurement were used to calculate the blood flow in the voxel. The data from all three measurements were combined to calculate the oxygen consumption in the voxel. The values of cerebral blood flow and oxygen consumption calculated with 17O NMR techniques agree reasonably well with values calculated for a similar region of the cat brain using autoradiographic techniques. © 1991 Academic Press, Inc. Copyright © 1991 Wiley‐Liss, Inc., A Wiley Company
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页码：313 / 319
页数：7
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