DEVELOPMENT INVITRO OF CYTOTOXIC LYMPHOCYTES AGAINST MURINE CYTOMEGALO-VIRUS

被引：8

作者：

HO, M ^{[1
]}

ASHMAN, RB ^{[1
]}

机构：

[1] AUSTRALIAN NATL UNIV,JOHN CURTIN SCH MED RES,DEPT MICROBIOL,CANBERRA 2601,ACT,AUSTRALIA

来源：

AUSTRALIAN JOURNAL OF EXPERIMENTAL BIOLOGY AND MEDICAL SCIENCE | 1979年 / 57卷 / AUG期

关键词：

D O I：

10.1038/icb.1979.42

中图分类号：

R-3 [医学研究方法]; R3 [基础医学];

学科分类号：

1001 ;

摘要：

Lymphocytes cytotoxic for mouse embryo fibroblasts (MEF) infected with murine cytomegalovirus (MCMV) were produced by in vitro culture of 'memory' spleen cells with UV-irradiated, MCMV-infected, MEF. Cytotoxic lymphocytes were developed from spleen cells of mice 10 to 240 days after infection with MCMV. The cytotoxic cells carried the theta and Ly 2 antigens, and were H-2 restricted in the recognition of infected target cells.

引用

页码：425 / 428

页数：4

共 15 条

[1] INVITRO PRIMARY INDUCTION OF CYTOTOXIC T CELLS AGAINST VIRUS-INFECTED SYNGENEIC CELLS [J].

BLANDEN, RV ;

KEES, U ;

DUNLOP, MBC .

JOURNAL OF IMMUNOLOGICAL METHODS, 1977, 16 (01) :73-89

[2] RESISTANCE TO MURINE CYTOMEGALOVIRUS LINKED TO MAJOR HISTOCOMPATIBILITY COMPLEX OF MOUSE [J].

CHALMER, JE ;

MACKENZIE, JS ;

STANLEY, NF .

JOURNAL OF GENERAL VIROLOGY, 1977, 37 (OCT) :107-114

[3] PROCEDURE FOR REMOVING RED-CELLS AND DEAD CELLS FROM LYMPHOID-CELL SUSPENSIONS [J].

DAVIDSON, WF ;

PARISH, CR .

JOURNAL OF IMMUNOLOGICAL METHODS, 1975, 7 (2-3) :291-299

[4] VIRUS-INFECTIONS AFTER TRANSPLANTATION IN MAN - BRIEF REVIEW [J].

HO, M .

ARCHIVES OF VIROLOGY, 1977, 55 (1-2) :1-24

[5]

KELSEY DK, 1978, J IMMUNOL, V121, P464

[6] ENHANCEMENT OF INFECTIVITY OF MURINE CYTOMEGALOVIRUS IN VITRO BY CENTRIFUGAL INOCULATION [J].

OSBORN, JE ;

WALKER, DL .

JOURNAL OF VIROLOGY, 1968, 2 (09) :853-+

[7] CELL-MEDIATED IMMUNE-RESPONSE TO ECTROMELIA VIRUS-INFECTION SECONDARY RESPONSE INVITRO - SPECIFICITY, NATURE OF EFFECTOR AND RESPONDER CELLS AND REQUIREMENTS FOR INDUCTION OF ANTIGENIC CHANGES IN STIMULATOR CELLS [J].

PANG, T ;

BLANDEN, RV .

AUSTRALIAN JOURNAL OF EXPERIMENTAL BIOLOGY AND MEDICAL SCIENCE, 1976, 54 (JUN) :253-264

[8] COOPERATION BETWEEN MOUSE T-CELL SUBPOPULATIONS IN CELL-MEDIATED RESPONSE TO A NATURAL POXVIRUS PATHOGEN [J].

PANG, T ;

MCKENZIE, IFC ;

BLANDEN, RV .

CELLULAR IMMUNOLOGY, 1976, 26 (02) :153-159

[9] T-CELL-MEDIATED CYTOTOXICITY AGAINST HERPES-SIMPLEX VIRUS-INFECTED TARGET-CELLS [J].

PFIZENMAIER, K ;

STARZINSKIPOWITZ, A ;

ROLLINGHOFF, M ;

FALKE, D ;

WAGNER, H .

NATURE, 1977, 265 (5595) :630-632

[10] CYTOTOXIC LYMPHOCYTE-T RESPONSE TO MURINE CYTOMEGALOVIRUS-INFECTION [J].

QUINNAN, GV ;

MANISCHEWITZ, JE ;

ENNIS, FA .

NATURE, 1978, 273 (5663) :541-543

← 1 2 →