Adalimumab Induced or Provoked MS in Patient with Autoimmune Uveitis: A Case Report and Review of the Literature

被引：7

作者：

Alsukhni, Rana Alnasser ^{[1
]}

Jriekh, Ziena ^{[2
]}

Aboras, Yasmin ^{[1
]}

机构：

[1] Aleppo Univ Hosp, Div Neurol, Dept Internal Med, Aleppo, Syria

[2] Aleppo Univ Hosp, Div Rheumatol, Dept Internal Med, Aleppo, Syria

来源：

CASE REPORTS IN MEDICINE | 2016年 / 2016卷

关键词：

D O I：

10.1155/2016/1423131

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Anti-tumor necrosis factor alpha (anti-TNF-alpha) agents have been widely used in the field of autoimmune diseases and have proved decisive efficacy and relative safety. Data concerning their adverse effects has been lately describing central nervous system (CNS) demyelination process at escalating basis. Case Presentation. A 23-year-old male with autoimmune uveitis and a family history of multiple sclerosis (MS) developed two neurological attacks, after Adalimumab infusion, simultaneously with several cerebral lesions on magnetic resonance imaging (MRI). Hence the diagnosis of Adalimumab induced MS was suspected. Conclusion. This case is reported to tell physicians to be cautious when using anti-TNF-alpha in patients with family history ofMS and to reconsider the risk of MS in patients with autoimmune diseases.

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页数：6

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