ACTIVE HUMAN IMMUNODEFICIENCY VIRUS PROTEASE IS REQUIRED FOR VIRAL INFECTIVITY

被引:1350
作者
KOHL, NE [1 ]
EMINI, EA [1 ]
SCHLEIF, WA [1 ]
DAVIS, LJ [1 ]
HEIMBACH, JC [1 ]
DIXON, RAF [1 ]
SCOLNICK, EM [1 ]
SIGAL, IS [1 ]
机构
[1] MERCK SHARP & DOHME RES LABS,DEPT VIRUS & CELL BIOL,W POINT,PA 19486
关键词
D O I
10.1073/pnas.85.13.4686
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
引用
收藏
页码:4686 / 4690
页数:5
相关论文
共 25 条
[1]   PRODUCTION OF ACQUIRED IMMUNODEFICIENCY SYNDROME-ASSOCIATED RETROVIRUS IN HUMAN AND NONHUMAN CELLS TRANSFECTED WITH AN INFECTIOUS MOLECULAR CLONE [J].
ADACHI, A ;
GENDELMAN, HE ;
KOENIG, S ;
FOLKS, T ;
WILLEY, R ;
RABSON, A ;
MARTIN, MA .
JOURNAL OF VIROLOGY, 1986, 59 (02) :284-291
[2]   GAG POLYPROTEIN PRECURSORS OF RAUSCHER MURINE LEUKEMIA-VIRUS [J].
ARCEMENT, LJ ;
KARSHIN, WL ;
NASO, RB ;
ARLINGHAUS, RB .
VIROLOGY, 1977, 81 (02) :284-297
[3]   GENOMIC HETEROGENEITY OF AIDS RETROVIRAL ISOLATES FROM NORTH-AMERICA AND ZAIRE [J].
BENN, S ;
RUTLEDGE, R ;
FOLKS, T ;
GOLD, J ;
BAKER, L ;
MCCORMICK, J ;
FEORINO, P ;
PIOT, P ;
QUINN, T ;
MARTIN, M .
SCIENCE, 1985, 230 (4728) :949-951
[4]  
COFFIN J, 1982, MOL BIOL TUMOR VIRUS, P261
[5]   A DELETION MUTATION IN THE 5' PART OF THE POL GENE OF MOLONEY MURINE LEUKEMIA-VIRUS BLOCKS PROTEOLYTIC PROCESSING OF THE GAG AND POL POLYPROTEINS [J].
CRAWFORD, S ;
GOFF, SP .
JOURNAL OF VIROLOGY, 1985, 53 (03) :899-907
[6]   HUMAN IMMUNODEFICIENCY VIRUS PROTEASE EXPRESSED IN ESCHERICHIA-COLI EXHIBITS AUTOPROCESSING AND SPECIFIC MATURATION OF THE GAG PRECURSOR [J].
DEBOUCK, C ;
GORNIAK, JG ;
STRICKLER, JE ;
MEEK, TD ;
METCALF, BW ;
ROSENBERG, M .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1987, 84 (24) :8903-8906
[7]   MOLECULAR CHARACTERIZATION OF A POLYMERASE MUTANT HUMAN-IMMUNODEFICIENCY-VIRUS [J].
GENDELMAN, HE ;
THEODORE, TS ;
WILLEY, R ;
MCCOY, J ;
ADACHI, A ;
MERVIS, RJ ;
VENKATESAN, S ;
MARTIN, MA .
VIROLOGY, 1987, 160 (02) :323-329
[8]   INTRINSIC GTPASE ACTIVITY DISTINGUISHES NORMAL AND ONCOGENIC RAS-P21 MOLECULES [J].
GIBBS, JB ;
SIGAL, IS ;
POE, M ;
SCOLNICK, EM .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA-BIOLOGICAL SCIENCES, 1984, 81 (18) :5704-5708
[9]   CHARACTERIZATION OF RIBOSOMAL FRAMESHIFTING IN HIV-1 GAG-POL EXPRESSION [J].
JACKS, T ;
POWER, MD ;
MASIARZ, FR ;
LUCIW, PA ;
BARR, PJ ;
VARMUS, HE .
NATURE, 1988, 331 (6153) :280-283
[10]   MURINE LEUKEMIA-VIRUS MATURATION - PROTEASE REGION REQUIRED FOR CONVERSION FROM IMMATURE TO MATURE CORE FORM AND FOR VIRUS INFECTIVITY [J].
KATOH, I ;
YOSHINAKA, Y ;
REIN, A ;
SHIBUYA, M ;
ODAKA, T ;
OROSZLAN, S .
VIROLOGY, 1985, 145 (02) :280-292