POSTTRANSLATIONAL PROCESSING OF THE RAS SUPERFAMILY OF SMALL GTP-BINDING PROTEINS

被引：98
作者：
NEWMAN, CMH [1 ]
MAGEE, AI [1 ]
机构：
[1] NATL INST MED RES,EUKARYOT MOLEC GENET LAB,LONDON NW7 1AA,ENGLAND
来源：
BIOCHIMICA ET BIOPHYSICA ACTA | 1993年 / 1155卷 / 01期
基金：
英国医学研究理事会;
关键词：
D O I：
10.1016/0304-419X(93)90023-6
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
[No abstract available]
引用
收藏
页码：79 / 96
页数：18
相关论文
共 221 条
[71]   THE BIOCHEMISTRY OF RAS P21 [J].
GRAND, RJA ;
OWEN, D .
BIOCHEMICAL JOURNAL, 1991, 279 :609-631
[72]   LOCALIZATION OF RAL, A SMALL MR GTP-BINDING PROTEIN, TO COLLECTING DUCT CELLS IN BOVINE AND RAT-KIDNEY [J].
GUPTA, A ;
BASTANI, B ;
CHARDIN, P ;
HRUSKA, KA .
AMERICAN JOURNAL OF PHYSIOLOGY, 1991, 261 (06) :F1063-F1070
[73]   CHARACTERIZATION OF AN ACYLTRANSFERASE ACTING ON P21N-RAS PROTEIN IN A CELL-FREE SYSTEM [J].
GUTIERREZ, L ;
MAGEE, AI .
BIOCHIMICA ET BIOPHYSICA ACTA, 1991, 1078 (02) :147-154
[74]   POST-TRANSLATIONAL PROCESSING OF P21RAS IS 2-STEP AND INVOLVES CARBOXYL-METHYLATION AND CARBOXY-TERMINAL PROTEOLYSIS [J].
GUTIERREZ, L ;
MAGEE, AI ;
MARSHALL, CJ ;
HANCOCK, JF .
EMBO JOURNAL, 1989, 8 (04) :1093-1098
[75]   RAS-RELATED GTPASES AND THE CYTOSKELETON [J].
HALL, A .
MOLECULAR BIOLOGY OF THE CELL, 1992, 3 (05) :475-479
[76]   THE CELLULAR FUNCTIONS OF SMALL GTP-BINDING PROTEINS [J].
HALL, A .
SCIENCE, 1990, 249 (4969) :635-640
[77]   A POLYBASIC DOMAIN OR PALMITOYLATION IS REQUIRED IN ADDITION TO THE CAAX MOTIF TO LOCALIZE P21RAS TO THE PLASMA-MEMBRANE [J].
HANCOCK, JF ;
PATERSON, H ;
MARSHALL, CJ .
CELL, 1990, 63 (01) :133-139
[78]   ALL RAS PROTEINS ARE POLYISOPRENYLATED BUT ONLY SOME ARE PALMITOYLATED [J].
HANCOCK, JF ;
MAGEE, AI ;
CHILDS, JE ;
MARSHALL, CJ .
CELL, 1989, 57 (07) :1167-1177
[79]   A CAAX OR A CAAL MOTIF AND A 2ND SIGNAL ARE SUFFICIENT FOR PLASMA-MEMBRANE TARGETING OF RAS PROTEINS [J].
HANCOCK, JF ;
CADWALLADER, K ;
PATERSON, H ;
MARSHALL, CJ .
EMBO JOURNAL, 1991, 10 (13) :4033-4039
[80]   METHYLATION AND PROTEOLYSIS ARE ESSENTIAL FOR EFFICIENT MEMBRANE-BINDING OF PRENYLATED P21K-RAS(B) [J].
HANCOCK, JF ;
CADWALLADER, K ;
MARSHALL, CJ .
EMBO JOURNAL, 1991, 10 (03) :641-646
3456789101112