COMPARATIVE MAPPING OF THE IMPRINTED U2AFBPL GENE ON MOUSE CHROMOSOME-11 AND HUMAN-CHROMOSOME-5

被引：12
|
作者：
KALCHEVA, I
PLASS, C
SAIT, S
EDDY, R
SHOWS, T
WATKINSCHOW, D
CAMPER, S
SHIBATA, H
UEDA, T
TAKAGI, N
HAYASHIZAKI, Y
CHAPMAN, V
机构：
[1] ROSWELL PK CANC INST,DEPT MOLEC & CELLULAR BIOL,BUFFALO,NY 14263
[2] ROSWELL PK CANC INST,DEPT HUMAN GENET,BUFFALO,NY
[3] UNIV MICHIGAN,SCH MED,DEPT HUMAN GENET,ANN ARBOR,MI
[4] INST PHYS & CHEM RES,TSUKUBA LIFE SCI CTR,GENE BANK,TSUKUBA,IBARAKI 305,JAPAN
[5] NIIGATA UNIV,MOLEC GENET RES LAB,NIIGATA,JAPAN
[6] HOKKAIDO UNIV,GRAD SCH ENVIRONM EARTH SCI,DIV BIOL SCI,KITA KU,SAPPORO,HOKKAIDO 060,JAPAN
来源：
CYTOGENETICS AND CELL GENETICS | 1995年 / 68卷 / 1-2期
关键词：
D O I：
10.1159/000133881
中图分类号：
Q2 [细胞生物学];
学科分类号：
071009 ; 090102 ;
摘要：
The genetic map location of the recently discovered imprinted gene U2afbpL has been verified and refined in several mouse crosses. RI strain analysis had previously shown that the gene is located on mouse chromosome 11. This assignment has been verified using interspecific backcrosses. Moreover, the location of the gene relative to a fixed order of markers in the proximal region of mouse chromosome 11 has been established. The location of the gene on mouse chromosome 11 corresponds to a homologous linkage group that is conserved on human chromosome 5q. The location of the human homologue has been determined using both somatic cell hybrid genetic analysis and fluorescence in situ hybridization. These analyses have mapped the human locus U2AFBPL to human chromosome 5q23-->q31.
引用
收藏
页码：19 / 24
页数：6
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