LYMPHOPENIA AND LYMPHOCYTE-TRANSFORMATION IN ALCOHOLICS

被引：39
作者：
YOUNG, GP
VANDERWEYDEN, MB
ROSE, IS
DUDLEY, FJ
机构：
[1] Monash University Department of Medicine, Alfred Hospital, Prahran, 3181, Victoria
来源：
EXPERIENTIA | 1979年 / 35卷 / 02期
关键词：
D O I：
10.1007/BF01920656
中图分类号：
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号：
07 ; 0710 ; 09 ;
摘要：
The basis of peripheral blood lymphopenia observed in patients with chronic alcoholism and liver disease was investigated by examining the effect of sera of these patients on in vitro transformation of normal human peripheral blood lymphocytes. A positive correlation was demonstrated between the serum inhibition of phytohaemagglutinin- and pokeweed mitogen-induced transformation and the degree of lymphopenia. Thus serum factors may contribute to the observed lymphopenia by inhibiting lymphocyte production in vivo. © 1979 Birkhäuser Verlag.
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页码：268 / 269
页数：2
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