INTRADURAL GRANULOCYTIC SARCOMA PRESENTING AS A LUMBAR RADICULOPATHY - CASE-REPORT

被引：23

作者：

KIM, FSC ^{[1
]}

RUTKA, JT ^{[1
]}

BERNSTEIN, M ^{[1
]}

RESCH, L ^{[1
]}

WARNER, E ^{[1
]}

PANTALONY, D ^{[1
]}

机构：

[1] TORONTO WESTERN HOSP, DEPT PATHOL, 399 BATHURST ST, TORONTO M5T 2S8, ONTARIO, CANADA

来源：

JOURNAL OF NEUROSURGERY | 1990年 / 72卷 / 04期

关键词：

chloroma; dorsal nerve root; granulocytic sarcoma;

D O I：

10.3171/jns.1990.72.4.0663

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Granulocytic sarcoma usually occurs in the setting of leukemia and myeloproliferative disorders. Rarely, it can occur in isolation at various anatomical sites without hematological evidence of leukemia. The unique case of an elderly man presenting with right L2-3 radiculopathy is described. Intradural granulocytic sarcoma of the L-2 and L-3 nerve roots with extradural extension was found at surgery and he was treated with incomplete resection and antileukemic chemotherapy. Local recurrence at 3 months was treated with irradiation. Granulocytic sarcoma is frequently misdiagnosed and invariably progresses to acute leukemia. The chloroacetic acid esterase, granulocyte immunohistochemical markers, and electron microscopy appearance can aid in diagnosis. The prognosis is improved with initial aggressive antileukemic chemotherapy and local irradiation.

引用

页码：663 / 667

页数：5

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