PSEUDORELAPSE IN ACUTE MYELOMONOCYTIC LEUKEMIA AFTER HIGH-DOSE METHYLPREDNISOLONE

被引：2

作者：

ALBAYRAK, D

机构：

[1] Department of Pediatric Hematology, Medical Faculty, Ondokuzmayis University, Samsun

来源：

LEUKEMIA RESEARCH | 1994年 / 18卷 / 01期

关键词：

LEUKEMIA; MYELOMONOCYTIC; METHYLPREDNISOLONE; HIGH DOSE; RELAPSE;

D O I：

10.1016/0145-2126(94)90010-8

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

High dose methylprednisolone (HDMP) has been used both in induction treatment and in leukopenia of acute leukemia. We report the case of a 14-year-old girl with acute myelomonocytic leukemia (AMML) who developed a pseudorelapse after receiving an oral HDMP trial (30 mg/kg/day PO in the morning for 15 days) to overcome neutropenia. She presented with severe bone pain at the end of treatment. Bone marrow examination revealed 53% young promyelocytes (some with a large nucleolus), 2% myeloblast, 5% monocyte, and increased cellularity. Bone pain and promyelocytes regressed spontaneously while maintenance treatment continues. We advise that a pseudorelapse must be borne in mind after MDMP and probably GM-CSF treatments in acute leukaemias.

引用

页码：61 / 62

页数：2

共 4 条

[1] ACCELERATION OF LEUKOCYTE RECOVERY BY ADMINISTRATION OF SHORT-COURSE HIGH-DOSE METHYLPREDNISOLONE IN CHILDREN WITH ACUTE LYMPHOBLASTIC-LEUKEMIA [J].