POLONIUM METABOLISM IN ADULT FEMALE BABOONS

被引：25
作者：
FELLMAN, A
RALSTON, L
HICKMAN, D
AYRES, L
COHEN, N
机构：
[1] S COHEN & ASSOCIATES INC,MCLEAN,VA 22101
[2] LAWRENCE LIVERMORE NATL LAB,LIVERMORE,CA 94550
[3] NYU,MED CTR,INST ENVIRONM MED,AJ LANZA LAB,TUXEDO PK,NY 10987
来源：
RADIATION RESEARCH | 1994年 / 137卷 / 02期
关键词：
D O I：
10.2307/3578817
中图分类号：
Q [生物科学];
学科分类号：
07 ; 0710 ; 09 ;
摘要：
The biokinetics of polonium in nonhuman primates (Papio anubis) has been studied after intravenous injection of 210Po citrate. The urinary excretion of polonium in the baboon could be described by a single exponential function with a half-time of 15.6 days. Excretion fractions of polonium were found to be markedly different from those reported for other species, including humans. Polonium-210 was found to be distributed throughout the soft tissues of the baboon with 29% of the injected polonium being deposited in liver, 7% in kidneys and 0.6% in spleen. Retention of polonium in all tissues exhibited single exponential functions; however, the biological half-times were variable, ranging from 15 to 50 days.
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页码：238 / 250
页数：13
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