ISOLATION, CLONING AND SEQUENCE-ANALYSIS OF THE CDNA FOR THE ALPHA-SUBUNIT OF HUMAN CHORIONIC-GONADOTROPIN

被引:296
作者
FIDDES, JC
GOODMAN, HM
机构
[1] Howard Hughes Medical Institute Laboratory, Department of Biochemistry and Biophysics, University of California, San Francisco
关键词
D O I
10.1038/281351a0
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
A 621-base pair fragment of the cDNA for the α-subunit of human chorionic gonadotropin has been isolated by cloning in a plasmid vector, and the complete nucleotide sequence determined. The entire coding region, including the 24-amino acid pre-sequence and most of the untranslated regions, are present in the fragment. © 1979 Nature Publishing Group.
引用
收藏
页码:351 / 356
页数:6
相关论文
共 54 条
[1]  
Acher R, 1976, Ciba Found Symp, V41, P31
[3]  
BAHL OP, 1977, FED PROC, V36, P2119
[4]  
BELLISARIO R, 1973, J BIOL CHEM, V248, P6796
[5]  
BIRKEN S, 1977, J BIOL CHEM, V252, P5386
[6]  
BOIME I, 1976, J BIOL CHEM, V251, P820
[7]  
BOIME I, ANN NY ACAD SCI
[8]   CONSTRUCTION AND CHARACTERIZATION OF NEW CLONING VEHICLES .2. MULTIPURPOSE CLONING SYSTEM [J].
BOLIVAR, F ;
RODRIGUEZ, RL ;
GREENE, PJ ;
BETLACH, MC ;
HEYNEKER, HL ;
BOYER, HW ;
CROSA, JH ;
FALKOW, S .
GENE, 1977, 2 (02) :95-113
[9]  
Caneld R. E., 1976, PEPTIDE HORMONES, P299
[10]  
CASTLEMAN B, 1960, NEW ENGL J MED, V263, P965