ANTI-ANNEXIN-V ANTIBODY IN SYSTEMIC LUPUS-ERYTHEMATOSUS PATIENTS WITH LUPUS ANTICOAGULANT AND/OR ANTICARDIOLIPIN ANTIBODY

被引：116
作者：
MATSUDA, J
SAITOH, N
GOHCHI, K
GOTOH, M
TSUKAMOTO, M
机构：
[1] Department of Medicine, Teikyo University School of Medicine, Tokyo
来源：
AMERICAN JOURNAL OF HEMATOLOGY | 1994年 / 47卷 / 01期
关键词：
ANTI-ANNEXIN V ANTIBODY; ANTICARDIOLIPIN ANTIBODY; LUPUS ANTICOAGULANT; BETA(2)-GLYCOPROTEIN 1;
D O I：
10.1002/ajh.2830470112
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
We investigated anti-annexin V antibody (aANX) in patients with systemic lupus erythematosus (SLE), and correlated to positivity with lupus anticoagulant (LA)/anticardiolipin antibody (aCL). aANX was positive in 12/47 SLE patients (26%), including 7 with beta(2)-glycoprotein 1 (GPI)-dependent aANX. The positivity of aANX was higher in patients with aCL (19%) and LA/aCL (50%) than in those without LA/aCL (10%). From these results, it is concluded that aANX is an autoantibody closely related to LA/aCL, and can be a possible new risk marker for thrombosis. (C) 1994 Wiley-Liss, Inc.
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页码：56 / 58
页数：3
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