POSTSYNTHETIC TRANSFORMATIONS OF OLIGODEOXYNUCLEOTIDES ORIGINATED AT 6-METHYLTHIO-PURINE SITE

被引：10
作者：
BURDZY, A
SKALSKI, B
BIALA, E
KOWALEWSKI, A
PASZYC, S
ADAMIAK, RW
机构：
[1] POLISH ACAD SCI,INST BIOORGAN CHEM,POZNAN,POLAND
[2] ADAM MICKIEWICZ UNIV POZNAN,FAC CHEM,POZNAN,POLAND
来源：
NUCLEOSIDES & NUCLEOTIDES | 1995年 / 14卷 / 3-5期
关键词：
D O I：
10.1080/15257779508012515
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
New route to oligodeoxynucleotides labeled with fluorescent luminarine was explored. Regioselective oxidation of 6-methylthio-purines to 6-methylsulphoxides reactive toward pyridine was achieved. Upon UV irradiation of 6-pyridinium-purines oligonucleotide cleavage instead of phototransformation to luminarine was observed.
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页码：979 / 982
页数：4
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