Usual Complication after Radiotherapy of Jaws for Carcinoma: Osteoradionecrosis

被引:0
作者
Dholakia, Kartik [1 ]
Dhanak, Rahul [1 ]
Makwana, Tushar [1 ]
机构
[1] Karnavati Sch Dent, Dept Oral & Maxillofacial Surg, Gandhinagar, Gujarat, India
关键词
Osteoradionecrosis; maxilla; mandible; radiotherapy; Pentoxiphylline;
D O I
暂无
中图分类号
Q [生物科学];
学科分类号
07 ; 0710 ; 09 ;
摘要
Background: Osteoradionecrosis (ORN) is the death of bone due to radiation. The bone dies because of damage to its blood vessels caused by the radiation. Radiation provides high cure rates, but has also called increasing attention to its side effects. Osteoradionecrosis (ORN) is one of the most severe and serious complications of head and neck cancer treatment. A new theory for the pathogenesis of ORN has proposed that damage to bone is caused by radiation-induced fibrosis. Here there is a case which was operated conservatively and after 8 months of follow up no recurrence was observed.
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页码:77 / 81
页数:5
相关论文
共 24 条
[1]   Hyperbaric oxygen therapy for radionecrosis of the jaw:: A randomized, placebo-controlled, double-blind trial from the ORN96 Study Group [J].
Annane, D ;
Depondt, J ;
Aubert, P ;
Villart, M ;
Géhanno, P ;
Gajdos, P ;
Chevret, S .
JOURNAL OF CLINICAL ONCOLOGY, 2004, 22 (24) :4893-4900
[2]   OSTEONECROSIS IN PATIENTS TREATED WITH DEFINITIVE RADIOTHERAPY FOR SQUAMOUS-CELL CARCINOMAS OF ORAL CAVITY AND NASOPHARYNX AND OROPHARYNX [J].
BEDWINEK, JM ;
SHUKOVSKY, LJ ;
FLETCHER, GH ;
DALEY, TE .
RADIOLOGY, 1976, 119 (03) :665-667
[3]   POST-RADIATION DENTAL EXTRACTIONS - A REVIEW OF THE LITERATURE AND A REPORT OF 72 EPISODES [J].
BEUMER, J ;
HARRISON, R ;
SANDERS, B ;
KURRASCH, M .
HEAD & NECK SURGERY, 1983, 6 (01) :581-586
[4]   OSTEORADIONECROSIS OF MANDIBLE RESULTING FROM EXTERNAL MEGAVOLTAGE RADIATION-THERAPY [J].
CHENG, VST ;
WANG, CC .
RADIOLOGY, 1974, 112 (03) :685-689
[5]   Major healing of refractory mandible osteoradionecrosis after treatment combining pentoxifylline and tocopherol: A phase II trial [J].
Delanian, S ;
Depondt, J ;
Lefaix, JL .
HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK, 2005, 27 (02) :114-123
[6]   The radiation-induced fibroatrophic process: therapeutic perspective via the antioxidant pathway [J].
Delanian, S ;
Lefaix, JL .
RADIOTHERAPY AND ONCOLOGY, 2004, 73 (02) :119-131
[7]   THE CONSERVATIVE MANAGEMENT OF OSTEORADIONECROSIS OF THE MANDIBLE WITH ULTRASOUND THERAPY [J].
HARRIS, M .
BRITISH JOURNAL OF ORAL & MAXILLOFACIAL SURGERY, 1992, 30 (05) :313-318
[8]   Hyperfractionated, accelerated chemoradiation with concurrent mitomycin-C and cisplatin in locally advanced head and neck cancer, a phase I/II study [J].
Hehr, Thomas ;
Classen, Johannes ;
Welz, Stefan ;
Ganswindt, Ute ;
Scheithauer, Heike ;
Koitschev, Asen ;
Bamberg, Michael ;
Budach, Wilfried .
RADIOTHERAPY AND ONCOLOGY, 2006, 80 (01) :33-38
[9]   Paradigm shifts in the management of osteoradionecrosis of the mandible [J].
Jacobson, Adam S. ;
Buchbinder, Daniel ;
Hu, Kenneth ;
Urken, Mark L. .
ORAL ONCOLOGY, 2010, 46 (11) :795-801
[10]   Resolution of pain and complete healing of mandibular osteoradionecrosis using pentoxifylline and tocopherol: a case report [J].
Kahenasa, Nora ;
Sung, Eric C. ;
Nabili, Vishad ;
Kelly, Jim ;
Garrett, Neal ;
Nishimura, Ichiro .
ORAL SURGERY ORAL MEDICINE ORAL PATHOLOGY ORAL RADIOLOGY, 2012, 113 (04) :E18-E23