A TOTAL SYNTHESIS OF (-)-SLAFRAMINE FROM (+)-CIS-(2R,3S)-3-HYDROXYPROLINE

被引：29
|
作者：
KNIGHT, DW
SIBLEY, AW
机构：
[1] Department of Chemistry, Nottingham, NG7 2RD, University Park
来源：
TETRAHEDRON LETTERS | 1993年 / 34卷 / 41期
关键词：
D O I：
10.1016/0040-4039(93)88117-2
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A total synthesis of the naturally occurring indolizidine (-)-Slaframine 4 has been achieved, starting from the cis-3-hydroxyproline derivative 1, in which a key step is a Julia olefination reaction using the dianion derived from the beta-aminosulfone 5.
引用
收藏
页码：6607 / 6610
页数：4
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