NMR-STUDIES OF THE INTERACTIONS OF NEUTRAL POLYMERS WITH UNILAMELLAR VESICLES

被引:2
作者
LABONTE, R [1 ]
GAO, ZS [1 ]
KWAK, JCT [1 ]
机构
[1] DALHOUSIE UNIV,DEPT CHEM,HALIFAX B3H 4J3,NS,CANADA
关键词
BINDING; ION PERMEATION; PHOSPHOLIPID VESICLES; POLY(ETHYLENE OXIDE); POLY(PROPYLENE OXIDE);
D O I
10.1016/0927-7757(93)80332-9
中图分类号
O64 [物理化学(理论化学)、化学物理学];
学科分类号
070304 ; 081704 ;
摘要
The NMR paramagnetic relaxation method is used to investigate the interactions between poly(ethylene oxide) (PEO) and poly(propylene oxide) (PPO) and small unilamellar vesicles (SUVs) of phospholipids. The results indicate the PEO does not interact with phospholipid vesicles; it is located exclusively in the bulk water phase. Low molecular weight PPO polymers distribute between the aqueous and lipid phases. The vesicles remain impermeable to Pr3+ ions when PEO or PPO is present.
引用
收藏
页码:271 / 275
页数:5
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