Adult Stem Cell Responses to Nanostimuli

被引：31
作者：
Tsimbouri, Penelope M. [1 ]
机构：
[1] Univ Glasgow, Coll Med Vet & Life Sci, Ctr Cell Engn, Inst Mol Cell & Syst Biol, Joseph Black Bldg, Glasgow G12 8QQ, Lanark, Scotland
来源：
JOURNAL OF FUNCTIONAL BIOMATERIALS | 2015年 / 6卷 / 03期
关键词：
stem cells; stem cell niche; MSC; nanoforces; nanotopography; nanovibration; mechanotransduction; ECM; cell adhesion;
D O I：
10.3390/jfb6030598
中图分类号：
R318 [生物医学工程];
学科分类号：
0831 ;
摘要：
Adult or mesenchymal stem cells (MSCs) have been found in different tissues in the body, residing in stem cell microenvironments called "stem cell niches". They play different roles but their main activity is to maintain tissue homeostasis and repair throughout the lifetime of an organism. Their ability to differentiate into different cell types makes them an ideal tool to study tissue development and to use them in cell-based therapies. This differentiation process is subject to both internal and external forces at the nanoscale level and this response of stem cells to nanostimuli is the focus of this review.
引用
收藏
页码：598 / 622
页数：25
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