BOVINE PAPILLOMAVIRUS E1 PROTEIN CAN, BY ITSELF, EFFICIENTLY DRIVE MULTIPLE ROUNDS OF DNA-SYNTHESIS IN-VITRO

被引：34
作者：
BONNEANDREA, C
SANTUCCI, S
CLERTANT, P
机构：
来源：
JOURNAL OF VIROLOGY | 1995年 / 69卷 / 05期
关键词：
D O I：
10.1128/JVI.69.5.3201-3205.1995
中图分类号：
Q93 [微生物学];
学科分类号：
071005 ; 100705 ;
摘要：
Bovine papillomavirus E1 protein was found to be as efficient as the simian virus 40 large T antigen in initiating DNA synthesis in a cell-free system derived from COS1 cells. Multiple rounds of DNA synthesis occur, initiated at the bovine papillomavirus type 1 origin. Therefore, E1 functions in vitro as a lytic virus initiator.
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页码：3201 / 3205
页数：5
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