Pregnancy and breast cancer in the first trimester. A case report and literature review

Introduction: Breast cancer is the second most common cause of oncological death around the world, only surpassed by lung cancer. In addition, breast cancer is one of the most commonly diagnosed malignancies during pregnancy, followed by blood and skin cancers. Until recently, chemotherapy and radiation during pregnancy were considered incompatible with normal fetal development. Here we present the case of a pregnant female diagnosed with stage IIB (T3N1) infiltrating ductal breast adenocarcinoma at 13 weeks of gestation. Based on Adjuvant Online, the risk of recurrence is thought to be 65%, but with chemotherapy and hormone therapy systemic treatment, this risk falls to 22%. For this reason, it was decided to start therapy at 20 weeks of gestation. At 37 weeks, after hematologic evaluation, labour was electively induced. A baby weighing 2,900 grams, with no obvious congenital abnormalities and Apgar scores of 9 and 9 was born. The baby had no immediate post-natal complications and was taken to the newborn nursery. Conclusions: In the presence of a palpable or symptomatic mass in a pregnant patient, it is warranted to investigate the aetiology of the abnormality. The surgical management of pregnant patients is safe and must be done in a multidisciplinary way. Pharmacological management with cancer drugs must be a choice in this disease and the benefits must be evaluated in relationship with the gestation age of the patient (C) 2016 Elsevier Espana, S.L.U. All rights reserved.