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- [21] RATIONAL DESIGN OF POTENT NONPEPTIDAL HIV PROTEASE INHIBITORSABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 1995, 210 : 27 - MEDIGHOSH, AKCHEN, YXU, YBCHO, WHBUTHOD, JHOLLAND, LEWALTERS, DE
- [22] HIGHLY DIASTEREOSELECTIVE REACTION OF A CHIRAL, NON-RACEMIC AMIDE ENOLATE WITH (S)-GLYCIDYL TOSYLATE - SYNTHESIS OF THE ORALLY-ACTIVE HIV-1 PROTEASE INHIBITOR L-735,524TETRAHEDRON LETTERS, 1994, 35 (05) : 673 - 676ASKIN, DENG, KKROSSEN, KPURICK, RMWELLS, KMVOLANTE, RPREIDER, PJ
- [23] CRYSTAL-STRUCTURE OF HIV-1 PROTEASE IN COMPLEX WITH VX-478, A POTENT AND ORALLY BIOAVAILABLE INHIBITOR OF THE ENZYMEJOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1995, 117 (03) : 1181 - 1182KIM, EEBAKER, CTDWYER, MDMURCKO, MARAO, BGTUNG, RDNAVIA, MA
- [24] Orally bioavailable highly potent HIV protease inhibitors against PI-resistant virusBIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2005, 15 (23) : 5311 - 5314Lu, ZJBohn, JRano, TRutkowski, CASimcoe, ALOlsen, DBSchleif, WACarella, AGabryelski, LJin, LXLin, JHEmini, EChapman, KTata, JR
- [25] Structure-based discovery of tipranavir disodium (PNU-140690E): A potent, orally bioavailable, nonpeptidic HIV protease inhibitorBIOPOLYMERS, 1999, 51 (01) : 51 - 58Thaisrivongs, SStrohbach, JW
- [26] Design, synthesis, and biological evaluation of a potent and orally bioavailable FGFRs inhibitor for fibrotic treatmentEUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2025, 285Yue, LinTan, ZuiWei, WeiLiu, HongyaoXue, TaixiongSu, XingpingWu, XiuliXie, YutingLi, PeilinWang, DoudouLiu, ZhihaoGan, CailingYe, Tinghong
- [27] Discovery of a Pyrimidinedione Derivative as a Potent and Orally Bioavailable Axl InhibitorJOURNAL OF MEDICINAL CHEMISTRY, 2021, 64 (07) : 3956 - 3975Zhang, HefengPeng, XiaDai, YangShao, JingweiJi, YinchunSun, YimingLiu, BoCheng, XuAi, JingDuan, Wenhu
- [28] POTENT, ORALLY BIOAVAILABLE HIV-1 PROTEASE INHIBITORS CONTAINING NONCODED D-AMINO ACIDSBIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 1995, 5 (23) : 2897 - 2902MUNROE, JESHEPHERD, TAJUNGHEIM, LNHORNBACK, WJHATCH, SDMUESING, MAWISKERCHEN, MASU, KSCAMPANALE, KMBAXTER, AJCOLACINO, JM
- [29] Discovery of Raltegravir, a potent, selective orally bioavailable HIV-integrase inhibitor for the treatment of HIV-AIDS infectionJOURNAL OF MEDICINAL CHEMISTRY, 2008, 51 (18) : 5843 - 5855Summa, VincenzoPetrocchi, AlessiaBonelli, FabioCrescenzi, BenedettaDonghi, MonicaFerrara, MarcoFiore, FabrizioGardelli, CristinaPaz, Odalys GonzalezHazuda, Daria J.Jones, PhilipKinzel, OlafLaufer, RalphMonteagudo, EdithMuraglia, EsterNizi, EmanuelaOrvieto, FedericaPace, PaolaPescatore, GiovannaScarpelli, RitaStillmock, KaraWitmer, Marc V.Rowley, Michael
- [30] Design and synthesis of bicyclic pyrimidinones as potent and orally bioavailable HIV-1 integrase inhibitorsJOURNAL OF MEDICINAL CHEMISTRY, 2008, 51 (04) : 861 - 874Muraglia, EsterKinzel, OlafGardelli, CristinaCrescenzi, BenedettaDonghi, MonicaFerrara, MarcoNizi, EmanuelaOrvieto, FedericaPescatore, GiovannaLaufer, RalphGonzalez-Paz, OdalysDi Marco, AnnaliseFiore, FabrizioMonteagudo, EdithFonsi, MassimilianoFelock, Peter J.Rowley, MichaelSumma, Vincenzo