CORRELATION OF ISOMERIC FATTY-ACIDS IN HUMAN ADIPOSE-TISSUE WITH CLINICAL RISK-FACTORS FOR CARDIOVASCULAR-DISEASE

被引：75

作者：

HUDGINS, LC ^{[1
]}

HIRSCH, J ^{[1
]}

EMKEN, EA ^{[1
]}

机构：

[1] USDA ARS,NO REG RES CTR,PEORIA,IL 61604

来源：

AMERICAN JOURNAL OF CLINICAL NUTRITION | 1991年 / 53卷 / 02期

关键词：

TRANS FATTY ACIDS; CIS FATTY ACIDS; ADIPOSE TISSUE FATTY ACIDS; HEART DISEASE; ATHEROSCLEROSIS; HYPERLIPIDEMIA; HYDROGENATED VEGETABLE OIL; HYPERTENSION; OBESITY;

D O I：

10.1093/ajcn/53.2.474

中图分类号：

R15 [营养卫生、食品卫生]; TS201 [基础科学];

学科分类号：

100403 ;

摘要：

The relationships between the adipose tissue concentrations of 19 geometric and positional fatty acid isomers and 10 cardiovascular disease risk factors were determined in 76 free-living adult males. The percentages for trans isomers (total xBAR +/- SD 4.14 +/- 0.97%) and cis isomers (total xBAR +/- SD 2.91 +/- 0.34%) in adipose tissue generally agreed with dietary estimates based on the consumption of hydrogenated oils. A major exception was the percentage of 11c-18:1, which was twofold higher in adipose tissue. The total level of fatty acid isomers in adipose tissue or a factor (derived by factor analysis) that was representative of isomers of dietary origin was not significantly correlated with the cardiovascular risk factors. Only three trans isomers (11t-18:1, 12t-18:1, and 5t-14:1) and three cis isomers (11c-18:1, 13c-18:1, and 7c-16:1) were weakly correlated either positively or negatively with age, body mass index, plasma and lipoprotein cholesterol, and/or blood pressure (P < 0.05, r > 0.231).

引用

页码：474 / 482

页数：9

共 60 条

[1] ORIGIN OF CIS-9, TRANS-11-OCTADECADIENOIC AND TRANS-9, TRANS-11-OCTADECADIENOIC ACIDS IN THE DEPOT FAT OF PRIMATES FED A DIET RICH IN LARD AND CORN-OIL AND IMPLICATIONS FOR THE HUMAN DIET [J].

ACKMAN, RG ;

EATON, CA ;

SIPOS, JC ;

CREWE, NF .

CANADIAN INSTITUTE OF FOOD SCIENCE AND TECHNOLOGY JOURNAL-JOURNAL DE L INSTITUT CANADIEN DE SCIENCE ET TECHNOLOGIE ALIMENTAIRES, 1981, 14 (02) :103-107

[2] SYNTHESIS OF CIS AND TRANS METHYL 8-OCTADECENOATE-D2 AND 13-OCTADECENOATE-D2 AND D4 ISOMERS [J].