Ping-pong gaze secondary to monoamine oxidase inhibitor overdose

被引:5
作者
Attaway, Amy [1 ]
Sroujieh, Laila [2 ]
Mersfelder, Tracey L. [4 ]
Butler, Christopher [3 ]
Ouellette, Daniel [3 ]
机构
[1] Case Western Reserve Univ, Univ Hosp, Dept Pulm Crit Care, Cleveland, OH 44106 USA
[2] Metrohlth Med Ctr, Dept Pulm Crit Care, Cleveland, OH USA
[3] Henry Ford Hlth Syst, Pulm Crit Care, Detroit, MI USA
[4] Ferris State Univ, Borgess Hosp, Dept Pharm, Kalamazoo, MI USA
关键词
Monoamine oxidase inhibitor toxicity; phenelzine; ping pong gaze; short-cycle periodic alternating gaze;
D O I
10.4103/0976-500X.179360
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
An infrequent manifestation of monoamine oxidase inhibitor (MAOI) toxicity is "ping-pong gaze" (PPG). We describe the case of a 26-year-old female who was found unresponsive after taking 40 tablets of phenelzine. On presentation to the hospital, her eyes were moving in characteristic "ping pong" fashion. After 6 hours her gaze terminated. The following day her neurologic exam was benign and she had no long-term sequelae. While the etiology of PPG is unknown, it is most often seen with irreversible structural brain damage. However, a detailed literature review revealed that previous cases of MAOI toxicity where the patient survived have all had complete neurologic recovery.
引用
收藏
页码:34 / 37
页数:4
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