CIRCULAR FORMS OF DNA SYNTHESIZED BY ROUS-SARCOMA VIRUS INVITRO

被引：8

作者：

CLAYMAN, CH ^{[1
]}

MOSHARRAFA, ET ^{[1
]}

ANDERSON, DL ^{[1
]}

FARAS, AJ ^{[1
]}

机构：

[1] VIRGINIA POLYTECH INST & STATE UNIV,DEPT BIOL,BLACKSBURG,VA 24061

来源：

SCIENCE | 1979年 / 206卷 / 4418期

关键词：

D O I：

10.1126/science.91199

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Electron microscopic analysis of the DNA product synthesized by detergent-disrupted preparations of Rous sarcoma virus in vitro revealed the presence of several interesting molecular forms including covalently closed circular DNA. The identification of such circular DNA indicates that virions of retroviruses contain all the components necessary to facilitate the complete synthesis of mature forms of viral DNA and therefore provide a useful system to delineate the molecular mechanisms involved in their synthesis. Copyright © 1979 AAAS.

引用

页码：582 / 584

页数：3

共 25 条

[1] RETROVIRUSES [J].

BISHOP, JM .

ANNUAL REVIEW OF BIOCHEMISTRY, 1978, 47 :35-88

[2] INVITRO SYNTHESIS OF INFECTIOUS TRANSFORMING DNA BY THE AVIAN-SARCOMA VIRUS REVERSE-TRANSCRIPTASE [J].

CLAYMAN, CH ;

MOSHARRAFA, E ;

FARAS, AJ .

JOURNAL OF VIROLOGY, 1979, 29 (01) :242-249

[3] TERMINAL REDUNDANCY AND ORIGIN OF REPLICATION OF ROUS-SARCOMA VIRUS-RNA [J].

COFFIN, JM ;

HASELTINE, WA .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1977, 74 (05) :1908-1912

[4] RNASE H HYDROLYSIS OF 5'-TERMINUS OF AVIAN-SARCOMA VIRUS GENOME DURING REVERSE TRANSCRIPTION [J].

COLLETT, MS ;

DIERKS, P ;

PARSONS, JT ;

FARAS, AJ .

NATURE, 1978, 272 (5649) :181-184

[5] INVITRO TRANSCRIPTION OF DNA FROM 70S RNA OF ROUS-SARCOMA VIRUS - IDENTIFICATION AND CHARACTERIZATION OF VARIOUS SIZE CLASSES OF DNA TRANSCRIPTS [J].

COLLETT, MS ;

FARAS, AJ .

JOURNAL OF VIROLOGY, 1975, 16 (05) :1220-1228

[6] EVIDENCE FOR CIRCULARIZATION OF AVIAN ONCORNAVIRUS RNA GENOME DURING PROVIRAL DNA-SYNTHESIS FROM STUDIES OF REVERSE TRANSCRIPTION INVITRO [J].

COLLETT, MS ;

FARAS, AJ .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1976, 73 (04) :1329-1332

[7] TRANSCRIPTION OF DNA FROM 70S RNA OF ROUS-SARCOMA VIRUS .1. IDENTIFICATION OF A SPECIFIC 4S RNA WHICH SERVES AS PRIMER [J].

DAHLBERG, JE ;

SAWYER, RC ;

TAYLOR, JM ;

FARAS, AJ ;

LEVINSON, WE ;

GOODMAN, HM ;

BISHOP, JM .

JOURNAL OF VIROLOGY, 1974, 13 (05) :1126-1133

[8]

DAVIS RW, 1971, METHOD ENZYMOL, V21, P413

[9] TRANSCRIPTION OF DNA FROM 70S RNA OF ROUS-SARCOMA VIRUS .2. STRUCTURE OF A 4S RNA PRIMER [J].

FARAS, AJ ;

DAHLBERG, JE ;

SAWYER, RC ;

HARADA, F ;

TAYLOR, JM ;

LEVINSON, WE ;

BISHOP, JM ;

GOODMAN, HM .

JOURNAL OF VIROLOGY, 1974, 13 (05) :1134-1142

[10] RNA-DIRECTED DNA-POLYMERASE OF ROUS-SARCOMA VIRUS - INITIATION OF SYNTHESIS WITH 70 S VIRAL-RNA AS TEMPLATE [J].

FARAS, AJ ;

TAYLOR, JM ;

LEVINSON, WE ;

GOODMAN, HM ;

BISHOP, JM .

JOURNAL OF MOLECULAR BIOLOGY, 1973, 79 (01) :163-183

← 1 2 3 →