ACID-CATALYZED HYDROLYSIS OF N-PHENYL-4-SUBSTITUTED-BENZOHYDROXAMIC ACIDS

被引：36

作者：

GHOSH, KK

GHOSH, S

机构：

[1] School of Studies in Chemistry, Pt. Ravishankar Shukla University

来源：

JOURNAL OF ORGANIC CHEMISTRY | 1994年 / 59卷 / 06期

关键词：

D O I：

10.1021/jo00085a028

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Acidity rate profiles have been established for the hydrolysis of some N-phenyl-4-substituted-benzohydroxamic acids 4-XC6H4(C=O)N(OH)C6H5 (X = H, CH3, OCH3, NO2, Cl, F) in sulfuric acid solutions in 20/80 (v/v) dioxane-water medium. Analysis of the data by the Cox-Yates excess acidity method and substitutent, temperature, and solvent isotope effects are all compatible with a changeover from an A-2 mechanism at low acidities to a predominantly A-1 mechanism at high acidities.

引用

页码：1369 / 1374

页数：6

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