EFFECT OF FOOD-INTAKE ON INSULIN RECEPTOR IN MAN

被引：27

作者：

DEPIRRO, R ^{[1
]}

BERTOLI, A ^{[1
]}

GRECO, AV ^{[1
]}

GELLI, AS ^{[1
]}

LAURO, R ^{[1
]}

机构：

[1] UNIV CATTOLICA SACRO CUORE,IST PATOL MED,ROME,ITALY

来源：

ACTA ENDOCRINOLOGICA | 1979年 / 90卷 / 03期

关键词：

D O I：

10.1530/acta.0.0900473

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Insulin binding to circulating monocytes was studied in 22 normal volunteers before and 1, 3 and 5 hr after a 1400 Kcal meal. Results indicate that 3 hr after food intake there is an increase in the specific cell binding fraction (P < 0.001) with a change in receptor affinity. Data emerging from the present study demonstrate that there are rapid changes in insulin receptor properties during the day. These changes probably play a role in the regulation of the hormonal and metabolic pattern in normal subjects.

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页码：473 / 480

页数：8

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