CHLOROQUINE RESISTANCE PRODUCED INVITRO IN AN AFRICAN STRAIN OF HUMAN MALARIA

被引：56
作者：
NGUYENDINH, P
TRAGER, W
机构：
来源：
SCIENCE | 1978年 / 200卷 / 4348期
关键词：
D O I：
10.1126/science.351801
中图分类号：
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号：
07 ; 0710 ; 09 ;
摘要：
After continuous cultivation in the presence of chloroquine, an African strain of the malaria parasite, Plasmodium falciparum, acquired resistance to the drug. The resistance was stable and comparable in vitro to that occurring naturally in a strain from Southeast Asia. This suggests that chloroquine resistance, absent until now in Africa, might arise in the future. Copyright © 1978 AAAS.
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页码：1397 / 1398
页数：2
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