PARATHYROID-HORMONE RELATED PROTEIN IN HYPERCALCEMIA OF HODGKINS-DISEASE

被引：7
作者：
BOLODEOKU, J
BASU, S
LAKHANI, S
DUNNE, F
RATCLIFFE, WA
CLARKE, M
BARRON, JL
机构：
[1] QUEEN ELIZABETH HOSP,WOLFSON RES LABS,BIRMINGHAM B15 2TH,W MIDLANDS,ENGLAND
[2] QUEEN ELIZABETH HOSP,DEPT HAEMATOL,BIRMINGHAM B15 2TH,W MIDLANDS,ENGLAND
[3] QUEEN ELIZABETH HOSP,DEPT MED,BIRMINGHAM B15 2TH,W MIDLANDS,ENGLAND
[4] QUEEN ELIZABETH HOSP,DEPT HISTOPATHOL,BIRMINGHAM B15 2TH,W MIDLANDS,ENGLAND
来源：
JOURNAL OF CLINICAL PATHOLOGY | 1992年 / 45卷 / 06期
关键词：
D O I：
10.1136/jcp.45.6.541
中图分类号：
R36 [病理学];
学科分类号：
100104 ;
摘要：
The role of parathyroid hormone related protein (PTHRP) as a humoral mediator of hypercalcaemia was investigated in a patient with lymphocyte depleted Hodgkin's disease during an episode of hypercalcaemia, using an immunohistochemical staining technique for PTHRP on the tumour tissue and an immunoradiometric (IRMA) assay for PTHRP1-86 on the patient's plasma. The plasma PTHRP was less than 0.23 pmol/l in the range found in normocalcaemic controls, and the immunohistochemical staining was not positive for protein. PTHRP did not have a role in the pathogenesis of hypercalcaemia in this patient.
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收藏
页码：541 / 542
页数：2
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