Pyrazole Carbohydrazide Derivatives of Pharmaceutical Interest

被引：40

作者：

Sousa Dias, Luiza Rosaria ^{[1
]}

Silva Salvador, Raquel Rocha ^{[1
]}

机构：

[1] Univ Fed Fluminense, Lab Quim Med LQMed, Fac Farm, Rua Mario Viana,523, BR-24241000 Niteroi, RJ, Brazil

来源：

PHARMACEUTICALS | 2012年 / 5卷 / 03期

关键词：

pyrazole; carbohydrazide; biological activity;

D O I：

10.3390/ph5030317

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

The main purpose of this paper is to provide an insight into the biological activities of pyrazole derivatives which contain the carbohydrazide moiety.

引用

页码：317 / 324

页数：8

共 35 条

[1] Synthesis of novel pyrazole derivatives and evaluation of their antidepressant and anticonvulsant activities [J].

Abdel-Aziz, Mohamed ;

Abuo-Rahma, Gamal El-Din A. ;

Hassan, Alaa A. .

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2009, 44 (09) :3480-3487

[2] Synthesis and leishmanicidal activities of 1-(4-X-phenyl)-N′-[(4-Y-phenyl)methylene]-1H-pyrazole-4-carbohydrazides [J].

Bernardino, AMR ;

Gomes, AO ;

Charret, KS ;

Freitas, ACC ;

Machado, GMC ;

Canto-Cavalheiro, MM ;

Leon, LL ;

Amaral, VF .

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2006, 41 (01) :80-87

[3] Effect of Oral Treatment with Pyrazole Carbohydrazide Derivatives against Murine Infection by Leishmania amazonensis [J].

Charret, Karen S. ;

Rodrigues, Raquel F. ;

Bernardino, Alice M. R. ;

Gomes, Adriana O. ;

Carvalho, Adriana V. ;

Canto-Cavalheiro, Marilene M. ;

Leon, Leonor ;

Amaral, Veronica F. .

AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE, 2009, 80 (04) :568-573

[4]

Chen HS, 2000, CHINESE J CHEM, V18, P596

[5]

Chornous V.A., 2001, PHARM CHEM J, V35, P203, DOI DOI 10.1023/A:1010432029236

[6] HETEROATOM ANALOGS OF BEMORADAN - CHEMISTRY AND CARDIOTONIC ACTIVITY OF 1,4-BENZOTHIAZINYLPYRIDAZINONES [J].

COMBS, DW ;

RAMPULLA, MS ;

DEMERS, JP ;

FALOTICO, R ;

MOORE, JB .

JOURNAL OF MEDICINAL CHEMISTRY, 1992, 35 (01) :172-176

[7]

DeSantAnna CMR, 1996, INT J QUANTUM CHEM, V60, P1835, DOI 10.1002/(SICI)1097-461X(1996)60:8<1835::AID-QUA11>3.0.CO

[8]

2-Z

[9] Synthesis and discovery of autophagy inducers for A549 and H460 lung cancer cells, novel 1-(2′-hydroxy-3′-aroxypropyl)-3-aryl-1H-pyrazole-5-carbohydrazide derivatives [J].

Fan, Chuan-Dong ;

Zhao, Bao-Xiang ;

Wei, Fang ;

Zhang, Gai-Hua ;

Dong, Wen-Liang ;

Miao, Jun-Ying .

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2008, 18 (14) :3860-3864

[10] A novel copper complex of salicylaldehyde pyrazole hydrazone induces apoptosis through up-regulating integrin β4 in H322 lung carcinoma cells [J].

Fan, ChuanDong ;

Su, Hua ;

Zhao, Jing ;

Zhao, BaoXiang ;

Zhang, ShangLi ;

Miao, JunYing .

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2010, 45 (04) :1438-1446

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