ASSOCIATION OF MULTINODULAR GOITER WITH BREAST-CARCINOMA - COWDENS-DISEASE

被引：9

作者：

MICHAELS, RD

SHAKIR, KMM

机构：

[1] USN,NATL MED CTR,DEPT INTERNAL MED,DIV ENDOCRINOL & METAB,BETHESDA,MD 20889

[2] UNIFORMED SERV UNIV HLTH SCI,DEPT MED,BETHESDA,MD 20814

来源：

JOURNAL OF ENDOCRINOLOGICAL INVESTIGATION | 1993年 / 16卷 / 11期

关键词：

COWDENS DISEASE; MULTINODULAR GOITER; BREAST CARCINOMA;

D O I：

10.1007/BF03348956

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Cowden's Disease or multiple hamartoma syndrome is an autosomal dominant genodermatosis associated with abnormalities of the breast, thyroid gland, gastrointestinal tract and genitourinary system. A large percentage of these patients have goiters or other thyroid abnormalities. Physicians should consider the diagnosis of Cowden's disease in patients presenting with thyroid disease and skin lesions such as papules or skin tags and if present these subjects should be screened for other malignancies associated with this disease.

引用

页码：909 / 911

页数：3

共 8 条

[1]

GENTRY W C JR, 1975, Birth Defects Original Article Series, V11, P137

[2] COWDEN DISEASE - A HEREDITARY POLYPOSIS SYNDROME DIAGNOSABLE BY MUCOCUTANEOUS INSPECTION [J].