Giant Basal Cell Carcinoma of the Lumbosacral Region: A Case Report and Literature Review

Objective: Although frequently regarded as a low grade malignancy, basal cell carcinoma (BCC) sometimes shows aggressive behavior. Giant BCC is defined as a lesion greater then 5 centimeter. Material and Methods: The authors described the diagnosis and treatment protocol of giant BCC, involving lumbosacral region without any local or distant metastasis. Also the authors went through a thorough a retrospective literature research of giant BCCs in terms of frequency and treatment. Results: Giant BCCs are biologically more aggressive; however, patient's negligence is a key factor for the tumor size. International medical database (PubMed) search reveals 253 giant BCCs with the most commonly seen site as the face and back area. However perianal BCCs are seen lower then 1%. Conclusion: In general, diagnosed giant BCCs account for lower then 1% of all BCCs. One must keep in mind this diagnosis to discard the metastasis rate among BCCs.