DNAS OF THE 2 MATING-TYPE ALLELES OF NEUROSPORA-CRASSA ARE HIGHLY DISSIMILAR

被引：155

作者：

GLASS, NL ^{[1
]}

VOLLMER, SJ ^{[1
]}

STABEN, C ^{[1
]}

GROTELUESCHEN, J ^{[1
]}

METZENBERG, RL ^{[1
]}

YANOFSKY, C ^{[1
]}

机构：

[1] STANFORD UNIV, DEPT BIOL SCI, STANFORD, CA 94305 USA

来源：

SCIENCE | 1988年 / 241卷 / 4865期

关键词：

D O I：

10.1126/science.2840740

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

The mating-type alleles A and .alpha. of Neurospora crassa control mating in the sexual cycle and function in establishing heterokaryon incompatibility in the vegetative cycle. The A and a alleles were cloned, and they were shown to encode both the sexual functions and vegetative incompatibility. The mating-type clones contain nonhomologous DNA segments that are flanked by common DNA sequences. Neurospora crassa and all heterothallic and pseudohomothallic Neurospora species contain a single copy of one mating-type sequence or the other within each haploid genome. The six known self-fertile homothallic isolates contain an A homolog, but only one species also contains a homologous sequence. Homothallism in these species is not due to mating-type switching, as it is in Saccharomyces cerevisiae.

引用

页码：570 / 573

页数：4

共 20 条

[1] A TECHNIQUE FOR RADIOLABELING DNA RESTRICTION ENDONUCLEASE FRAGMENTS TO HIGH SPECIFIC ACTIVITY [J].