ESTIMATION OF PLASMA RENIN CONCENTRATION USING RADIOIMMUNOASSAY OF ANGIOTENSIN-II

被引：31
|
作者：
POULSEN, K
机构：
来源：
SCANDINAVIAN JOURNAL OF CLINICAL & LABORATORY INVESTIGATION | 1969年 / 24卷 / 03期
关键词：
Angiotensin-I; Angiotensin-II; Converting enzyme; Enzyme assay; Enzyme kinetics; Plasma renin activity; Plasma renin concentration; Radio-immunoassay; Renin-substrate;
D O I：
10.3109/00365516909080165
中图分类号：
R-3 [医学研究方法]; R3 [基础医学];
学科分类号：
1001 ;
摘要：
Renin is measured by the rate of renin-substrate consumption with time. Renin-substrate is measured by conversion to angiotensin-II by excess of renin and converting enzyme. Characteristics: precisely determined angiotensinogen conc. during reaction, controlled converting enzyme activity, and eliminated influence of angiotensinases. The method, using 300 μl plasma, gives simultaneously renin concentration, renin activity, and renin-substrate concentration without chromatographic steps. Detection limit is 22 times lower than normal mean. Precision ± 6 %. © 1969 Informa UK Ltd All rights reserved: reproduction in whole or part not permitted.
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页码：291 / &
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