ERYTHEMA-MULTIFORME-LIKE, URTICARIAL PAPULAR AND PLAQUE ERUPTIONS FROM BUFEXAMAC - REPORT OF 4 CASES

被引：27
作者：
KOCH, P
BAHMER, FA
机构：
[1] Hautklinik der, Universitat des Saarlandes, Saar
来源：
CONTACT DERMATITIS | 1994年 / 31卷 / 02期
关键词：
BUFEXAMAC ADVERSE EFFECTS; NONSTEROIDAL ANTIINFLAMMATORY DRUGS; CONTACT DERMATITIS; DRUG-INDUCED SKIN REACTION; ERYTHEMA MULTIFORME; PATCH TESTING; URTICARIAL PAPULAR AND PLAQUE ERUPTIONS;
D O I：
10.1111/j.1600-0536.1994.tb01926.x
中图分类号：
R392 [医学免疫学];
学科分类号：
100102 ;
摘要：
4 patients developed an erythema-multiforme-like reaction following acute contact dermatitis from 2 different bufexamac-containing topical preparations. Histologically, the lesions did not show changes that were typical of erythema multiforme. Patch testing gave positive reactions to bufexamac at 1, 2, 3 and 4 days. The histological picture of 2 positive test reactions was suggestive of a drug reaction in the 1st, and of an acute eczematous reaction in the 2nd, case. A systemic allergic reaction with spread of lesions could have been involved, following percutaneous absorption of the allergen.
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页码：97 / 101
页数：5
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