GM CSF AND EOSINOPHIL CHEMOTACTIC FACTORS IN AN ACUTE LYMPHOBLASTIC-LEUKEMIA PATIENT WITH EOSINOPHILIA

被引：6

作者：

KITA, R ^{[1
]}

ENOKIHARA, H ^{[1
]}

NAGASHIMA, S ^{[1
]}

TSUNOGAKE, S ^{[1
]}

YAMATO, H ^{[1
]}

SAITO, K ^{[1
]}

FULUSAWA, S ^{[1
]}

SHISHIDO, H ^{[1
]}

FILKZNSHIMA, Y ^{[1
]}

FUKUDA, T ^{[1
]}

机构：

[1] DOKKYO UNIV,SCH MED,DEPT MED & CLIN IMMUNOL,MIBU,TOCHIGI,JAPAN

来源：

ACTA HAEMATOLOGICA | 1993年 / 90卷 / 03期

关键词：

ACUTE LYMPHOBLASTIC LEUKEMIA; EOSINOPHIL; EOSINOPHIL CHEMOTACTIC FACTOR; GM-CSF;

D O I：

10.1159/000204396

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

We describe a patient with common acute lymphoblastic leukemia associated with blood and cerebrospinal fluid (CSF) eosinophilia. Serum obtained at onset and conditioned medium prepared from T cells obtained at remission stimulated with interleukin-2 contained eosinophil colony stimulating activity (Eo-CSA), which was confirmed to be predominantly GM-CSF. Leukemic cell conditioned medium and serum obtained at remission contained no Eo-CSA. The CSF contained increased eosinophil chemotactic activity, however, this factor was not identified.

引用

页码：144 / 147

页数：4

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