INGESTED ARSENIC, KERATOSES, AND BLADDER-CANCER

被引：99

作者：

CUZICK, J ^{[1
]}

SASIENI, P ^{[1
]}

EVANS, S ^{[1
]}

机构：

[1] ROYAL LIVERPOOL HOSP, LIVERPOOL L69 3BX, ENGLAND

来源：

AMERICAN JOURNAL OF EPIDEMIOLOGY | 1992年 / 136卷 / 04期

关键词：

ARSENIC; BLADDER NEOPLASMS; KERATOSIS;

D O I：

10.1093/oxfordjournals.aje.a116514

中图分类号：

R1 [预防医学、卫生学];

学科分类号：

1004 ; 120402 ;

摘要：

A cohort of 478 patients treated with Fowler's solution (potassium arsenite) in Lancashire, England, during the period 1945-1969 and previously followed until January 1, 1980, was followed for an additional 11 years. A significant excess of bladder cancer mortality occurred (observed/expected ratio = 5/1.6; p = 0.05). No excess was found for other causes of death. In a subcohort of 142 patients examined for signs of arsenicism around 1970, all 11 subsequent cancer deaths occurred in those with signs of arsenicism (p = 0.0009).

引用

页码：417 / 421

页数：5

共 13 条

[1] A DOSE-RESPONSE ANALYSIS OF SKIN-CANCER FROM INORGANIC ARSENIC IN DRINKING-WATER [J].