THE EFFECTS OF PROLACTIN ON HUMAN SPERM CAPACITATION AND ACROSOME REACTION

被引:0
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作者
STOVALL, DW [1 ]
SHABANOWITZ, RB [1 ]
机构
[1] UNIV N CAROLINA,SCH MED,DEPT OBSTET & GYNECOL,DIV REPROD ENDOCRINOL & FERTIL,CHAPEL HILL,NC 27514
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中图分类号
R71 [妇产科学];
学科分类号
100211 ;
摘要
Objective: To study the effects of human prolactin (PRL) on human sperm capacitation and acrosome reaction. Design: Acrosome reactions were induced by the addition of follicular fluid (FF) and progesterone (P). Experiments were performed to determine time and dose-dependent effects of PRL on sperm capacitation, potentiation of the acrosome reaction, decapacitating effects, and potential for PRL to induce an acrosome reaction. Results: An average of 31.5% of spermatozoa underwent acrosome reaction with addition of FF and P. No time- or dose-dependent PRL effects on sperm capacitation or acrosome reaction were found (P > 0.05). Conclusion: Prolactin does not play an important role in human sperm capacitation or acrosome reaction.
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页码:960 / 966
页数:7
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