Radiotherapy for vestibular schwannoma: Review of recent literature results

被引:36
作者
Apicella, Giuseppina [1 ]
Paolini, Marina [1 ]
Deantonio, Letizia [1 ,2 ]
Masini, Laura [1 ]
Krengli, Marco [1 ,2 ,3 ]
机构
[1] Univ Hosp Maggiore della Carita, Div Radiotherapy, Corso Mazzini 18, I-28100 Novara, Italy
[2] Univ Piemonte Orientale, Dept Translat Med, Novara, Italy
[3] CNAO, Pavia, Italy
关键词
Vestibular schwannoma; Acoustic neuroma; Stereotactic radiosurgery; Radiotherapy;
D O I
10.1016/j.rpor.2016.02.002
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Background: The management of vestibular schwannoma is still a quite controversial issue and can include wait and see policy, surgery and radiotherapy, mainly with stereotactic technique. The purpose of this study is to review the results of recent clinical series treated by radiotherapy. Materials and methods: Literature search was performed by Pubmed and Scopus by using the words vestibular schwannoma, acoustic neuroma, radiotherapy, radiosurgery. Results: Management options of VS include wait and see, surgery and radiotherapy. In case of small lesions, literature data report local control rates higher than 90% after radio surgery (SRS) similar those of surgical techniques. Recent literature reviews show favourable functional outcome by using SRS. Several literature data support the use of fractionated stereotactic radiotherapy (FSRT) in case of large inoperable lesions. Conclusion: Radiotherapy plays a relevant role in the treatment of VS. In small-size lesions, SRS can guarantee similar local control and potentially better function outcome compared to surgery. In case of large and irregularly shaped lesions, FSRT can be the used when surgery is not feasible. (C) 2016 Greater Poland Cancer Centre. Published by Elsevier Sp. z o.o. All rights reserved.
引用
收藏
页码:399 / 406
页数:8
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