A SPECTROPHOTOMETRIC STUDY OF THE INTERACTION OF VO2+ WITH ADENINE IN NUCLEOTIDES

被引：23
作者：
WILLIAMS, PAM [1 ]
BARAN, EJ [1 ]
机构：
[1] NATL UNIV LA PLATA,FAC CIENCIAS EXACTAS,C CORREO 962,RA-1900 LA PLATA,ARGENTINA
来源：
JOURNAL OF INORGANIC BIOCHEMISTRY | 1992年 / 48卷 / 01期
关键词：
D O I：
10.1016/0162-0134(92)80048-Z
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
The interaction of VO2+ with adenosine-triphosphate (ATP), -diphosphate (ADP), and -monophosphate (AMP) has been studied as a function of pH by differential UV-absorption spectroscopy. It could be demonstrated that at pH > 3 an interaction of the cation with the adenine ring takes place in the case of the VO/ATP and VO/ADP systems. At pH less-than-or-equal-to 3 the metal-to-ligand interaction occurs only through the phosphate moieties of the nucleotides; this is also the behavior observed for the VO/AMP system, even at higher pH values. Results for the VO2+/P2O74- and VO2+/D-Ribose interactions are also presented.
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页码：15 / 19
页数：5
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