DEVELOPMENTAL REGULATION OF THYMOSIN-BETA-10 MESSENGER-RNA IN THE HUMAN BRAIN

被引：26
作者：
HALL, AK
机构：
[1] Urology Research Laboratory, Department of Surgery, University of Medicine and Dentistry, Newark
来源：
MOLECULAR BRAIN RESEARCH | 1991年 / 9卷 / 1-2期
关键词：
D O I：
10.1016/0169-328X(91)90146-O
中图分类号：
Q189 [神经科学];
学科分类号：
071006 ;
摘要：
A specific thymosin β10 cDNA restriction fragment was used to monitor thymosin β10 mRNA levels in the brain during normal human neuroembryogenesis. Northern analysis revealed a single hybridizing 600 nucleotide mRNA species which was abundant in embryonic/fetal human brain, yet absent in the adult tissue. These findings suggest that thymosin β10 must play an important role in early neuroembryogenesis. © 1991.
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页码：175 / 177
页数：3
相关论文
共 17 条
[1]   PATTERN OF CELL MIGRATION DURING CORTICAL HISTOGENESIS [J].
BERRY, M ;
EAYRS, JT ;
ROGERS, AW .
NATURE, 1964, 203 (494) :591-&
[2]  
CHOMCZYNSKI P, 1987, ANAL BIOCHEM, V162, P591
[3]   ISOLATION AND STRUCTURAL CHARACTERIZATION OF THYMOSIN-BETA-4 FROM A HUMAN MEDULLARY-THYROID CARCINOMA [J].
CONLON, JM ;
GRIMELIUS, L ;
WALLIN, G ;
THIM, L .
JOURNAL OF ENDOCRINOLOGY, 1988, 118 (01) :155-159
[4]   RETINOIC ACID CAUSES AN ANTEROPOSTERIOR TRANSFORMATION IN THE DEVELOPING CENTRAL NERVOUS-SYSTEM [J].
DURSTON, AJ ;
TIMMERMANS, JPM ;
HAGE, WJ ;
HENDRIKS, HFJ ;
DEVRIES, NJ ;
HEIDEVELD, M ;
NIEUWKOOP, PD .
NATURE, 1989, 340 (6229) :140-144
[5]  
FEINBERG AP, 1984, ANAL BIOCHEM, V137, P266
[6]   MOLECULAR-CLONING OF THE CDNA FOR RAT SPLEEN THYMOSIN BETA-10 AND THE DEDUCED AMINO-ACID-SEQUENCE [J].
GOODALL, GJ ;
HORECKER, BL .
ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS, 1987, 256 (01) :402-405
[7]  
HALL A K, 1989, Society for Neuroscience Abstracts, V15, P1328
[8]  
HALL AJ, UNPUB
[9]   THYMOSIN BETA-10 LEVELS IN DEVELOPING HUMAN BRAIN AND ITS REGULATION BY RETINOIC ACID IN THE HTB-10 NEUROBLASTOMA [J].
HALL, AK ;
HEMPSTEAD, J ;
MORGAN, JI .
MOLECULAR BRAIN RESEARCH, 1990, 8 (02) :129-135
[10]  
HALL AK, IN PRESS J NEUROCHEM
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