FERRIC REDUCTASES IN ESCHERICHIA-COLI - THE CONTRIBUTION OF THE HEMOGLOBIN-LIKE PROTEIN

被引：21

作者：

ESCHENBRENNER, M ^{[1
]}

COVES, J ^{[1
]}

FONTECAVE, M ^{[1
]}

机构：

[1] UNIV JOSEPH FOURIER,ETUD DYNAM & STRUCT SELECT LAB,CTR NATL RECH SCI,UNITE RECH ASSOCIEE 332,F-38041 GRENOBLE 9,FRANCE

来源：

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS | 1994年 / 198卷 / 01期

关键词：

D O I：

10.1006/bbrc.1994.1018

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The haemoglobin-like protein (HMP) of E. coli previously isolated as a dihydropteridine reductase was shown to be also a ferric citrate reductase. We demonstrate that, in fact, HMP is a flavin reductase and that its ferric reductase activity is a result of its ability to reduce free flavins. However, when compared to the two main ferric/flavin reductases of E. coli, i.e., the NAD(P)H: flavin oxidoreductase and the sulfite reductase, one can conclude that the contribution of HMP to iron reduction is negligible. © 1994 Academic Press, Inc.

引用

页码：127 / 131

页数：5

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