PRECOCIOUS PUBERTY ASSOCIATED WITH PRIMARY HYPO-THYROIDISM IN A MONGOL GIRL

被引:6
作者
HANCOCK, KW [1 ]
STITCH, SR [1 ]
CHAPMAN, C [1 ]
机构
[1] GEN INFIRM,DEPT NUCL MED,LEEDS LS1 3EX,W YORKSHIRE,ENGLAND
关键词
D O I
10.1111/j.1365-2265.1979.tb03115.x
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
A mongol child suffering from hypothyroidism who presented with precocious puberty is described. A presumptive diagnosis of idiopathic precocious puberty was first made and she was treated initially with medroxyprogesterone acetate, and later with cyproterone acetate. The diagnosis of primary hypothyroidism was made late because of misleading results of protein bound iodine estimations. Subsequently, thyroid medication resulted in a prompt return to the normal range of the previously elevated levels of plasma gonadotrophins, thyroid stimulating hormone and plasma and urinary oestrogens, but the serum prolactin remained elevated for several months after therapy was begun. Copyright © 1979, Wiley Blackwell. All rights reserved
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页码:611 / 618
页数:8
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