TOTAL SYNTHESIS OF ANALOGS OF TOPOSTIN-B, A DNA TOPOISOMERASE-I INHIBITOR .1. SYNTHESIS OF FRAGMENTS OF TOPOSTIN-B-1 ANALOGS

被引:9
|
作者
NOGUCHI, H [1 ]
AOYAMA, T [1 ]
SHIOIRI, T [1 ]
机构
[1] NAGOYA CITY UNIV,FAC PHARMACEUT SCI,MIZUHO KU,NAGOYA,AICHI 467,JAPAN
关键词
D O I
10.1016/0040-4020(95)00616-G
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
Synthesis of the right and left building blocks, 36 and 5, for the analog 3 of topostin B-1, an inhibitor of mammalian DNA topoisomerase I, has been achieved in a convenient manner.
引用
收藏
页码:10531 / 10544
页数:14
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