Autism Spectrum Disorder and intact executive functioning

被引:7
作者
Ferrara, R. [1 ]
Ansermet, F. [2 ,3 ,4 ]
Massoni, F. [5 ]
Petrone, L. [5 ]
Onofri, E. [5 ]
Ricci, P. [5 ]
Archer, T. [6 ]
Ricci, S. [5 ]
机构
[1] Unil Univ Lausanne, Fac Biol & Med, Doctoral Sch, Lausanne, Switzerland
[2] Univ Geneva, Fac Med, Child & Adolescent Psychiat, CH-1211 Geneva 4, Switzerland
[3] Univ Hosp Geneva, Dept Pediat, Dept Child & Adolescent Psychiat, Serv, Geneva, Switzerland
[4] Univ Geneva, Dept Psychiat, CH-1211 Geneva 4, Switzerland
[5] Univ Sapienza Rome, Dept Anat Sci Histol Legal Med & Locomotor Appara, Rome, Italy
[6] Univ Gothenburg, Dept Psychol, Gothenburg, Sweden
来源
CLINICA TERAPEUTICA | 2016年 / 167卷 / 05期
关键词
Autism; ASD; executive functioning; intact;
D O I
10.7417/CT.2016.1951
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Earliest notions concerning autism (Autism Spectrum Disorders, ASD) describe the disturbance in executive functioning. Despite altered definition, executive functioning, expressed as higher cognitive skills required complex behaviors linked to the prefrontal cortex, are defective in autism. Specific difficulties in children presenting autism or verbal disabilities at executive functioning levels have been identified. Nevertheless, the developmental deficit of executive functioning in autism is highly diversified with huge individual variation and may even be absent. The aim of the present study to examine the current standing of intact executive functioning intact in ASD. Results: Analysis of ASD populations, whether high-functioning, Asperger's or autism Broad Phenotype, studied over a range of executive functions including response inhibition, planning, cognitive flexibility, cognitive inhibition, and alerting networks indicates an absence of damage/impairment compared to the typically-developed normal control subjects. Conclusions: These findings of intact executive functioning in ASD subjects provide a strong foundation on which to construct applications for growth environments and the rehabilitation of autistic subjects.
引用
收藏
页码:96 / 101
页数:6
相关论文
共 65 条
  • [1] Adams N, 2001, J AUTISM DEV DISORD, V42, P1052
  • [2] American Psychiatric Association, 2013, DSM 5
  • [3] American Psychiatric Association, 2000, DSM IV TR DIAGN STAT
  • [4] Neurodegenerative Aspects in Vulnerability to Schizophrenia Spectrum Disorders
    Archer, Trevor
    Ricci, Serafino
    Garcia, Danilo
    Ricciardi, Max Rapp
    [J]. NEUROTOXICITY RESEARCH, 2014, 26 (04) : 400 - 413
  • [5] Working memory
    Baddeley, Alan
    [J]. CURRENT BIOLOGY, 2010, 20 (04) : R136 - R140
  • [6] Barkley RA, 2006, ATTENTION DEFICIT HY
  • [7] Baron-Cohen S, 1997, HDB AUTISM PERVASIVE, P880
  • [8] Interneuron Transcriptional Dysregulation Causes Frequency-Dependent Alterations in the Balance of Inhibition and Excitation in Hippocampus
    Bartley, Aundrea F.
    Lucas, Elizabeth K.
    Brady, Lillian J.
    Li, Qin
    Hablitz, John J.
    Cowell, Rita M.
    Dobrunz, Lynn E.
    [J]. JOURNAL OF NEUROSCIENCE, 2015, 35 (46) : 15276 - 15290
  • [9] Baumler G, 1985, FARBE WORT INTERFERE
  • [10] Burgess P., 1997, HAYLING BRIXTON TEST