THE ID GENE IS ACTIVATED BY SERUM BUT IS NOT REQUIRED FOR DEDIFFERENTIATION IN RAT VASCULAR SMOOTH-MUSCLE CELLS

被引：30
|
作者：
KEMP, PR
GRAINGER, DJ
SHANAHAN, CM
WEISSBERG, PL
METCALFE, JC
机构：
[1] UNIV CAMBRIDGE,ADDENBROOKES HOSP,SCH CLIN MED,CAMBRIDGE CB2 2QQ,ENGLAND
[2] UNIV CAMBRIDGE,DEPT BIOCHEM,CAMBRIDGE CB2 2PJ,ENGLAND
来源：
BIOCHEMICAL JOURNAL | 1991年 / 277卷
基金：
英国惠康基金;
关键词：
D O I：
10.1042/bj2770285
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Primary rat vascular smooth muscle cells cultured on fibronectin in the absence of serum lost smooth-muscle-specific myosin heavy chain but did not enter the cell cycle and proliferate until they were stimulated by serum. Under these conditions accumulation of Id mRNA occurred only in response to serum and was maximal during the G1 phase of the cycle.
引用
收藏
页码：285 / 288
页数：4
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