JUVENILE INTERVERTEBRAL-DISK CALCIFICATION - RECOGNITION, MANAGEMENT, AND PATHOGENESIS

被引:28
作者
DIAS, MS
PANG, D
机构
[1] UNIV PITTSBURGH, SCH MED, CHILDRENS HOSP PITTSBURGH, 1 CHILDRENS PL, PITTSBURGH, PA 15261 USA
[2] UNIV UTAH, SCH MED, DEPT NEUROL SURG, SALT LAKE CITY, UT 84112 USA
关键词
CHILDREN; INTERVERTEBRAL DISK; SPINAL CALCIFICATION;
D O I
10.1227/00006123-199101000-00018
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Juvenile intervertebral disc calcification is an uncommon disorder of childhood, characterized by calcification of the nucleus pulposus of one or more intervertebral discs. Calcification may remain dormant or subsequently become symptomatic. The symptoms include fever, malaise, and neck pain and are associated with an elevated erythrocyte sedimentation rate and, occasionally, leukocytosis. Although disc protrusion occurs in 38% of patients, neurological signs are distinctly uncommon. We report the case of a patient with a herniated T2-T3 calcified intervertebral disc and compressive myelopathy. Juvenile intervertebral disc calcification is generally a self-limiting disease that seldom requires an operation. The symptoms are transient, and resorption of the disc calcification is the rule once symptoms occur. Neither the cause of the disc calcification nor the trigger for the onset of symptoms is known. An inflammatory response within the disc appears to give rise to clinical symptoms and is associated with eventual resorption of the disc calcification.
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页码:130 / 135
页数:6
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